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Image Unavailable-BOSSBS-1077R-FITC

Anti-POU2F2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Beschreibung: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform OCT2.5 activates the U2 small nuclear RNA (snRNA) promoter. Isoforms OCT2.1, OCT2.2 and OCT2.3 activate octamer-containing promoters. Isoforms OCT2.4 and OCT2.5 repress some promoters and activate others. Isoform OCT2.7 is unable to bind to the octamer motif, but can still activate the beta-casein gene promoter at low levels.
Artikel-Nr: BOSSBS-1077R-FITC
VE: 1 * 100 µl
Lieferant: Bioss
Image Unavailable-BOSSBS-1077R-A647

Anti-POU2F2 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Beschreibung: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform OCT2.5 activates the U2 small nuclear RNA (snRNA) promoter. Isoforms OCT2.1, OCT2.2 and OCT2.3 activate octamer-containing promoters. Isoforms OCT2.4 and OCT2.5 repress some promoters and activate others. Isoform OCT2.7 is unable to bind to the octamer motif, but can still activate the beta-casein gene promoter at low levels.
Artikel-Nr: BOSSBS-1077R-A647
VE: 1 * 100 µl
Lieferant: Bioss
Image Unavailable-BOSSBS-1077R-A350

Anti-POU2F2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Beschreibung: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform OCT2.5 activates the U2 small nuclear RNA (snRNA) promoter. Isoforms OCT2.1, OCT2.2 and OCT2.3 activate octamer-containing promoters. Isoforms OCT2.4 and OCT2.5 repress some promoters and activate others. Isoform OCT2.7 is unable to bind to the octamer motif, but can still activate the beta-casein gene promoter at low levels.
Artikel-Nr: BOSSBS-1077R-A350
VE: 1 * 100 µl
Lieferant: Bioss
Image Unavailable-BOSSBS-1077R-A555

Anti-POU2F2 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Beschreibung: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform OCT2.5 activates the U2 small nuclear RNA (snRNA) promoter. Isoforms OCT2.1, OCT2.2 and OCT2.3 activate octamer-containing promoters. Isoforms OCT2.4 and OCT2.5 repress some promoters and activate others. Isoform OCT2.7 is unable to bind to the octamer motif, but can still activate the beta-casein gene promoter at low levels.
Artikel-Nr: BOSSBS-1077R-A555
VE: 1 * 100 µl
Lieferant: Bioss
Image Unavailable-BOSSBS-1077R-HRP

Anti-POU2F2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Beschreibung: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform OCT2.5 activates the U2 small nuclear RNA (snRNA) promoter. Isoforms OCT2.1, OCT2.2 and OCT2.3 activate octamer-containing promoters. Isoforms OCT2.4 and OCT2.5 repress some promoters and activate others. Isoform OCT2.7 is unable to bind to the octamer motif, but can still activate the beta-casein gene promoter at low levels.
Artikel-Nr: BOSSBS-1077R-HRP
VE: 1 * 100 µl
Lieferant: Bioss
Image Unavailable-BOSSBS-3816R-A647

Anti-POU5F1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Beschreibung: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP26. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Artikel-Nr: BOSSBS-3816R-A647
VE: 1 * 100 µl
Lieferant: Bioss
Image Unavailable-BOSSBS-1077R-CY3

Anti-POU2F2 Rabbit Polyclonal Antibody (Cy3®)

Beschreibung: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform OCT2.5 activates the U2 small nuclear RNA (snRNA) promoter. Isoforms OCT2.1, OCT2.2 and OCT2.3 activate octamer-containing promoters. Isoforms OCT2.4 and OCT2.5 repress some promoters and activate others. Isoform OCT2.7 is unable to bind to the octamer motif, but can still activate the beta-casein gene promoter at low levels.
Artikel-Nr: BOSSBS-1077R-CY3
VE: 1 * 100 µl
Lieferant: Bioss
Image Unavailable-BOSSBS-0483R-CY3

Anti-CENPA Rabbit Polyclonal Antibody (Cy3®)

Beschreibung: Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The four core histones, H2A, H2B, H3, and H4, assemble into an octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped around the octamer, forming a nucleosome, the basic subunit of chromatin. Histone modifications regulate DNA transcription, repair, recombination, and replication. The most commonly studied modifications are acetylation, phosphorylation, methylation, and ubiquitination. These modifications can alter local chromatin architecture, or recruit trans-acting factors that recognize specific histone modifications (the "histone code" hypothesis). Trimethylation of histone H3 on Lys9 (H3K9me3) is one of the most highly studied epigenetic marks. H3K9me3 functions in the repression of euchromatic genes, and in epigenetic control of heterochromatin assembly, most likely via acting as a recognition motif for the binding of chromatin-associated proteins, such as Swi6 or HP1Alpha/Beta. The enzymes responsible for H3K9me3 formation are SUV39H1 and SUV39H2.
Artikel-Nr: BOSSBS-0483R-CY3
VE: 1 * 100 µl
Lieferant: Bioss
Image Unavailable-BOSSBS-0483R

Anti-Centromeric histone H3-like Protein-2 Rabbit Polyclonal Antibody

Beschreibung: Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The four core histones, H2A, H2B, H3, and H4, assemble into an octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped around the octamer, forming a nucleosome, the basic subunit of chromatin. Histone modifications regulate DNA transcription, repair, recombination, and replication. The most commonly studied modifications are acetylation, phosphorylation, methylation, and ubiquitination. These modifications can alter local chromatin architecture, or recruit trans-acting factors that recognize specific histone modifications (the "histone code" hypothesis). Trimethylation of histone H3 on Lys9 (H3K9me3) is one of the most highly studied epigenetic marks. H3K9me3 functions in the repression of euchromatic genes, and in epigenetic control of heterochromatin assembly, most likely via acting as a recognition motif for the binding of chromatin-associated proteins, such as Swi6 or HP1Alpha/Beta. The enzymes responsible for H3K9me3 formation are SUV39H1 and SUV39H2.
Artikel-Nr: BOSSBS-0483R
VE: 1 * 100 µl
Lieferant: Bioss
Image Unavailable-BOSSBS-1111R-CY5

Anti-POU5F1 Rabbit Polyclonal Antibody (Cy5®)

Beschreibung: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Artikel-Nr: BOSSBS-1111R-CY5
VE: 1 * 100 µl
Lieferant: Bioss
Image Unavailable-BOSSBS-1111R-CY5.5

Anti-POU5F1 Rabbit Polyclonal Antibody (Cy5.5®)

Beschreibung: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Artikel-Nr: BOSSBS-1111R-CY5.5
VE: 1 * 100 µl
Lieferant: Bioss
Image Unavailable-BOSSBS-3816R-CY3

Anti-POU5F1 Rabbit Polyclonal Antibody (Cy3®)

Beschreibung: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP26. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Artikel-Nr: BOSSBS-3816R-CY3
VE: 1 * 100 µl
Lieferant: Bioss
Image Unavailable-BOSSBS-1111R-A555

Anti-POU5F1 Rabbit Polyclonal Antibody (Alexa Fluor® 555)

Beschreibung: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Artikel-Nr: BOSSBS-1111R-A555
VE: 1 * 100 µl
Lieferant: Bioss
Image Unavailable-BOSSBS-3816R-CY5.5

Anti-POU5F1 Rabbit Polyclonal Antibody (Cy5.5®)

Beschreibung: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP26. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Artikel-Nr: BOSSBS-3816R-CY5.5
VE: 1 * 100 µl
Lieferant: Bioss
Image Unavailable-BOSSBS-3816R-CY5

Anti-POU5F1 Rabbit Polyclonal Antibody (Cy5®)

Beschreibung: Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP26. Critical for early embryogenesis and for embryonic stem cell pluripotency.
Artikel-Nr: BOSSBS-3816R-CY5
VE: 1 * 100 µl
Lieferant: Bioss
Image Unavailable-BOSSBS-9392R-FITC

Anti-CHAF1A Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Beschreibung: Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci (By similarity). The CCR4-NOT complex functions as general transcription regulation complex. Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.
Artikel-Nr: BOSSBS-9392R-FITC
VE: 1 * 100 µl
Lieferant: Bioss
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