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N-Acetylneuraminic acid 97%

Lieferant: Apollo Scientific
Beschreibung: N-Acetylneuraminic acid 97%

Image Unavailable-19023-10MG

Supelco® Organic Reference Standard, N-Acetylneuraminic Acid

Artikel-Nr: (19023-10MG)
Lieferant: Merck
Beschreibung: Organic Standard, N-Acetylneuraminic acid
VE: 1 * 10 mg
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N-Acetylneuraminic acid 98%

Lieferant: Apollo Scientific
Beschreibung: N-Acetylneuraminic acid 98%

Image Unavailable-APOSOR8230T-5MG

5-Bromo-4-chloro-3-indolyl-α-D-N-acetylneuraminic acid

Artikel-Nr: (APOSOR8230T-5MG)
Lieferant: Apollo Scientific
Beschreibung: A substrate for the detection of sialidase-like enzyme,screening of enzymes, studying the physiological role of gangliosides, & for recombinant technologies.
VE: 1 * 5 mg
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N-Acetylneuraminic acid 97%

Lieferant: Thermo Scientific
Beschreibung: N-Acetylneuraminic acid 97%

Sicherheitsdatenblätter Zertifikate

Product Image-ACRO227040250

N-Acetylneuraminic acid 99%

Lieferant: Thermo Scientific
Beschreibung: Appearance: White to off-white Powder

Sicherheitsdatenblätter

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N-Acetylneuraminsäuremethylester 97% min

Lieferant: Apollo Scientific
Beschreibung: N-Acetylneuraminic acid methyl ester 97% min

Product Image-ENZOALX305010M250

N-Acetylneuraminic acid ≥97% (durch HPLC)

Artikel-Nr: (ENZOALX305010M250)
Lieferant: ENZO LIFE SCIENCES
Beschreibung: N-Acetylneuraminic acid ≥97% (durch HPLC)
VE: 1 * 250 mg

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2′-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid sodium salt hydrate

Lieferant: Apollo Scientific
Beschreibung: 2′-(4-Methylumbelliferyl)-α-D-N-acetylneuraminic acid sodium salt hydrate

Image Unavailable-APOSBICS0105-10MG

5-Bromo-4-chloro-3-indolyl α-D-N-acetylneuraminic acid sodium salt

Lieferant: Apollo Scientific
Beschreibung: 5-Bromo-4-chloro-3-indolyl α-D-N-acetylneuraminic acid sodium salt

Image Unavailable-1612619.

N-Acetylneuraminic Acid, Reference Standard

Artikel-Nr: (1612619.)
Lieferant: USP
Beschreibung: USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.
VE: 1 * 200 mg
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Anti-GLCNE Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-9882R-A680)
Lieferant: Bioss
Beschreibung: The bifunctional enzyme UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE/Mnk), or GLCNE, regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. GLCNE is required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumourigenicity and metastatic behavior of malignant cells. It is upregulated after PKC-dependent phosphorylation and is most abundantly expressed in liver and placenta. It is also expressed, to a lesser extent, in heart, brain, lung, kidney, skeletal muscle and pancreas. Defects in GLCNE are the cause of sialuria, inclusion body myopathy 2 (IBM2) and Nonaka myopathy (NM) or distal myopathy with rimmed vacuoles (DMRV). Sialuria is an autosomal dominant disorder caused by a lack of feedback inhibition of GLCNE by CMP-NeuAc, resulting in overproduction of NeuAc. It is characterised by an accumulation of free sialic acid in the cytoplasm and large quantities of neuraminic acid in the urine. Both IBM2 and NM/DMRV are autosomal recessive neuromuscular disorders characterised by adult onset, distal and proximal muscle weakness (especially in the legs) and a typical muscle pathology including filamentous inclusions and rimmed vacuoles.
VE: 1 * 100 µl
Image Unavailable-BOSSBS-9882R-A750

Anti-GLCNE Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Artikel-Nr: (BOSSBS-9882R-A750)
Lieferant: Bioss
Beschreibung: The bifunctional enzyme UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE/Mnk), or GLCNE, regulates and initiates biosynthesis of N-acetylneuraminic acid (NeuAc), a precursor of sialic acids. GLCNE is required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumourigenicity and metastatic behavior of malignant cells. It is upregulated after PKC-dependent phosphorylation and is most abundantly expressed in liver and placenta. It is also expressed, to a lesser extent, in heart, brain, lung, kidney, skeletal muscle and pancreas. Defects in GLCNE are the cause of sialuria, inclusion body myopathy 2 (IBM2) and Nonaka myopathy (NM) or distal myopathy with rimmed vacuoles (DMRV). Sialuria is an autosomal dominant disorder caused by a lack of feedback inhibition of GLCNE by CMP-NeuAc, resulting in overproduction of NeuAc. It is characterised by an accumulation of free sialic acid in the cytoplasm and large quantities of neuraminic acid in the urine. Both IBM2 and NM/DMRV are autosomal recessive neuromuscular disorders characterised by adult onset, distal and proximal muscle weakness (especially in the legs) and a typical muscle pathology including filamentous inclusions and rimmed vacuoles.
VE: 1 * 100 µl
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Anti-RBC Rabbit Polyclonal Antibody

Artikel-Nr: (ROCK103-4139)
Lieferant: Rockland Immunochemicals
Beschreibung: Anti-Chicken Red Blood Cell Antibody may be used in hemagglutination assays. Haemagglutination assay or HA is a method of quantification for viruses or bacteria by hemagglutination. Some viral families and many bacteria have envelope or surface proteins which are able to agglutinate (stick to) human or animal red blood cells (RBC) and bind to N-acetylneuraminic acid. As each of the agglutinating molecule attaches to multiple RBCs, a lattice-structure will form. Normally, a virus dilution (e.g. 2-fold from 1:4 to 1:4096) will be applied to an RBC dilution (e.g. 0.1% to 0.7% in steps of 0.2%) for approx. 30 min, often at 4° C, otherwise viruses with neuraminidase activity will detach the virus from the RBCs. Then the lattice forming parts will be counted and the titer calculated. The titer of a hemagglutination assay is determined by the last viable "lattice" structure found. This is because it is at the point where, if diluted anymore, the amount of Virus particles will be less than that of the RBCs and thus not be able to agglutinate them together. Anti-CHICKEN Red Blood Cell Antibody is used to sensitize erythrocytes and quantitate agglutination.
VE: 1 * 2 mL
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Anti-RBC Rabbit Polyclonal Antibody

Artikel-Nr: (ROCK113-4139)
Lieferant: Rockland Immunochemicals
Beschreibung: Anti-Sheep Red Blood Cell Antibody may be used in hemagglutination assays. Haemagglutination assay or HA is a method of quantification for viruses or bacteria by hemagglutination. Some viral families and many bacteria have envelope or surface proteins which are able to agglutinate (stick to) human or animal red blood cells (RBC) and bind to N-acetylneuraminic acid. As each of the agglutinating molecule attaches to multiple RBCs, a lattice-structure will form. Normally, a virus dilution (e.g. 2-fold from 1:4 to 1:4096) will be applied to an RBC dilution (e.g. 0.1% to 0.7% in steps of 0.2%) for approx. 30 min, often at 4° C, otherwise viruses with neuraminidase activity will detach the virus from the RBCs. Then the lattice forming parts will be counted and the titer calculated. The titer of a hemagglutination assay is determined by the last viable "lattice" structure found. This is because it is at the point where, if diluted anymore, the amount of Virus particles will be less than that of the RBCs and thus not be able to agglutinate them together. Anti-SHEEP Red Blood Cell Antibody is used to sensitize erythrocytes and quantitate agglutination.
VE: 1 * 2 mL
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N-Acetylneuraminic acid ≥98%, Pulver

Lieferant: MP Biomedicals
Beschreibung: Soluble in water.

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