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Image Unavailable-AGRIAS204496

Anti-Phy Mouse Monoclonal Antibody [clone: Oat-8]

Artikel-Nr: (AGRIAS204496)
Lieferant: Agrisera
Beschreibung: Phytochrome is a photomorphogenically active pigment that modulates plant growth and development with respect to incident light intensity and wavelength distribution. It exists in two forms: an inactive, red-absorbing form (Pr),4 and an active far-red-absorbing form (Pfr). When either absorbs light, it is photoconverted to the other.
VE: 1 * 100 µG

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Image Unavailable-AGRIAS204500

Anti-Phy Mouse Monoclonal Antibody [clone: Oat-25]

Artikel-Nr: (AGRIAS204500)
Lieferant: Agrisera
Beschreibung: Phytochrome is a photomorphogenically active pigment that modulates plant growth and development with respect to incident light intensity and wavelength distribution. It exists in two forms: an inactive, red-absorbing form (Pr),4 and an active far-red-absorbing form (Pfr). When either absorbs light, it is photoconverted to the other.
VE: 1 * 100 µG

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Image Unavailable-AGRIAS204502

Anti-Phy Mouse Monoclonal Antibody [clone: Pea-25]

Artikel-Nr: (AGRIAS204502)
Lieferant: Agrisera
Beschreibung: Phytochrome is a photomorphogenically active pigment that modulates plant growth and development with respect to incident light intensity and wavelength distribution. It exists in two forms: an inactive, red-absorbing form (Pr),4 and an active far-red-absorbing form (Pfr). When either absorbs light, it is photoconverted to the other.
VE: 1 * 100 µG

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Product Image-PRSI56-109

Anti-SUV39H1 Rabbit Polyclonal Antibody

Artikel-Nr: (PRSI56-109)
Lieferant: ProSci Inc.
Beschreibung: Similar to acetylation and phosphorylation, histone methylation at the N-terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity. Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET-domain-containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET-domain family, and another 17 make up the PR domain family that is related to the SET domain family. The retinoblastoma protein-interacting zinc finger geneRIZ1 is a tumor suppressor gene and a FOUNDING member of the PR domain family. RIZ1 inactivation is commonly found in many types of human cancers and occurs through loss of mRNA expression, frame shift mutation, chromosomal deletion, and missense mutation. RIZ1 is also a tumor susceptibility gene in mice. The loss of RIZ1 mRNA in human cancers was shown to associate with DNA methylation of its promoter CpG island. Methylation of the RIZ1 promoter strongly correlated with lost or decreased RIZ1 mRNA expression in breast, liver, colon, and lung cancer cell lines as well as in liver cancer tissues.
VE: 1 * 400 µl

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Image Unavailable-549-0596

SampliQ SPE-Kartuschen

Lieferant: Agilent
Beschreibung: Hochwertige SampliQ SPE-Produkte (Solid Phase Extraction) helfen dem Benutzer, Proben aus komplexen Matrizen sicher zu extrahieren und zu konzentrieren und sorgen so vom ersten Schritt an für schnelle, genaue und reproduzierbare Ergebnisse. Die SampliQ-Reihe umfasst Polymere, Silikat- und Nicht-Silikat-Optionen, um den spezifischen SPE-Anforderungen des Benutzers gerecht zu werden.

Product Image-PRSI7625

Anti-GLIPR1L1 Rabbit Polyclonal Antibody

Artikel-Nr: (PRSI7625)
Lieferant: ProSci Inc.
Beschreibung: The GLIPR1-like 1 protein (GLIPR1L1) gene is part of a p53 target gene cluster that includes the related proteins GLIPR1 and GLIPR1L2. GLIPR1L1 is similar to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. GLIPR1 is a tumor suppressor whose expression is regulated by p53. Unlike GLIPR1, GLIPR1L1 is expressed primarily in the testis and is thought to be involved in the binding of sperm to the oocyte complex.
VE: 1 * 100 µG
Image Unavailable-551-0309

Festphasenextraktionskartuschen, Bond Elut™ SCX

Lieferant: VARIAN
Beschreibung: Bond Elut™ SCX ist ein starker Kationenaustauscher mit einem sehr niedrigen pKa. Obwohl der pKa dem von Bond Elut™ PRS ähnelt, erhöht das Vorhandensein des Benzolrings in der Funktionsgruppe das Potenzial für unpolare Wechselwirkungen. Diese unpolare Eigenschaft wird besonders wichtig, wenn Ionenaustausch aus wässrigen Systemen durchgeführt wird, wo Selektivität gegenüber Verbindungen mit kationischem und unpolarem Charakter beobachtet wird.

Product Image-PRSI56-133

Anti-SETD7 Rabbit Polyclonal Antibody

Artikel-Nr: (PRSI56-133)
Lieferant: ProSci Inc.
Beschreibung: Similar to acetylation and phosphorylation, histone methylation at the N-terminal tail has emerged as an important role in regulating chromatin dynamics and gene activity. Histone methylation occurs on arginine and lysine residues and is catalyzed by two families of proteins, the protein arginine methyltransferase family and the SET-domain-containing methyltransferase family. Five members have been identified in the arginine methyltransferase family. About 27 are grouped into the SET-domain family, and another 17 make up the PR domain family that is related to the SET domain family. The retinoblastoma protein-interacting zinc finger geneRIZ1 is a tumor suppressor gene and a FOUNDING member of the PR domain family. RIZ1 inactivation is commonly found in many types of human cancers and occurs through loss of mRNA expression, frame shift mutation, chromosomal deletion, and missense mutation. RIZ1 is also a tumor susceptibility gene in mice. The loss of RIZ1 mRNA in human cancers was shown to associate with DNA methylation of its promoter CpG island. Methylation of the RIZ1 promoter strongly correlated with lost or decreased RIZ1 mRNA expression in breast, liver, colon, and lung cancer cell lines as well as in liver cancer tissues.
VE: 1 * 400 µl

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Product Image-PRSI7623

Anti-GLIPR1 Rabbit Polyclonal Antibody

Artikel-Nr: (PRSI7623)
Lieferant: ProSci Inc.
Beschreibung: The glioma pathogensis-related protein 1 (GLIPR1) is similar to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. GLIPR1 is a tumor suppressor whose expression is regulated by p53; its increased expression is associated with myelomocytic differentiation in macrophages, whereas decreased expression of this gene through gene methylation is associated with prostate cancer. The GLIPR1 gene is part of a p53 target gene cluster that includes GLIPR1L1 and GLIPR1L2, two highly homologous proteins whose expression patterns vary.
VE: 1 * 100 µG
Product Image-PRSI7639

Anti-GLIPR1L2 Rabbit Polyclonal Antibody

Artikel-Nr: (PRSI7639)
Lieferant: ProSci Inc.
Beschreibung: The GLIPR1-like 2 protein (GLIPR1L2) gene is part of a p53 target gene cluster that includes the related proteins GLIPR1 and GLIPR1L2. GLIPR1L2 is similar to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. GLIPR1 is a tumor suppressor whose expression is regulated by p53. Deletions of the GLIPR1/GLIPR1L1/GLIPR1L2 gene cluster have been observed in some multiple myeloma samples, suggesting that these proteins may also be involved in the pathogenesis of multiple myeloma.
VE: 1 * 100 µG
Image Unavailable-PRSI33-053

Anti-FABP7 Rabbit Polyclonal Antibody

Artikel-Nr: (PRSI33-053)
Lieferant: ProSci Inc.
Beschreibung: Fatty acid binding proteins (FABPs) are proteins that bind long-chain fatty acids and are thought to be involved in fatty acid uptake, transport, and metabolism. FABP7, also known as Brain lipid binding protein or BLBP, is essential for fetal brain development, and has been found to be important in brain and breast cancer, with opposing prognoses. It is a glioblastoma stem cell marker, highly expressed in the astrocyte-derived tumor cells and an indicator of poor prognosis. Abundant expression in basal-like/triple negative (ER-, PR-, HER2-) breast cancer cells, particularly with only nuclear expression, indicates a positive prognosis.
VE: 1 * 100 µG

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Product Image-PRSI7289

Anti-C1orf64 Rabbit Polyclonal Antibody

Artikel-Nr: (PRSI7289)
Lieferant: ProSci Inc.
Beschreibung: ERRF Antibody: The estrogen receptor-related factor (ERRF) is a recently identified protein whose expression is upregulated in multiple cell lines and primary breast cancer tumors. Increased ERRF expression was significantly associated with ER or progesterone receptor (PR) positivity even in HER2-negative tumors. This higher ERRF expression correlated with better disease-free survival and overall survival. In two ER-positive breast cancer cell lines, knockdown of ERRF suppressed cell growth in vitro and tumorigenesis in xenograft models, suggesting that ERRF plays a role in estrogen-ER-mediated breast cancer cell growth and may thus be a potential therapeutic target.
VE: 1 * 100 µG
Image Unavailable-MOLE17084825-500G

EPPS (HEPPS, 4-(2-Hydroxyethyl)-1-piperazinpropansulfonsäure)

Lieferant: Molekula
Beschreibung: EPPS (HEPPS, 4-(2-Hydroxyethyl)-1-piperazinpropansulfonsäure)

Image Unavailable-PRSI33-659

Anti-FOXA1 Mouse Monoclonal Antibody [clone: FOXA1/1512]

Artikel-Nr: (PRSI33-659)
Lieferant: ProSci Inc.
Beschreibung: FOXA1 is a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific transcripts such as albumin and transthyretin, and they also interact with chromatin as a pioneer factor. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver.<p>FOXA1 in breast cancer is highly correlated with ERalpha+, GATA3+, and PR+ protein expression as well as endocrine signaling. FOXA1 acts as a pioneer factor for ERa in ERalpha+ breast cancer, and its expression might identify ERalpha+ cancers that undergo rapid reprogramming of ERa signaling that is associated with poor outcomes and treatment resistance. Conversely, in ERalpha− breast cancer FOXA1 is highly correlated with low-grade morphology and improved disease free survival. FOXA1 is a downstream target of GATA3 in the mammary gland. Expression in ERalpha− cancers may identify a subset of tumors that is responsive to other endocrine therapies such as androgen receptor antagonist treatment. [Wiki].
VE: 1 * 100 µG

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Product Image-PRSI79-138

Anti-PGR Rabbit Polyclonal Antibody

Artikel-Nr: (PRSI79-138)
Lieferant: ProSci Inc.
Beschreibung: Progesterone receptors (PRs) are nuclear hormone receptors of the NR3C class, which also includes mineralocorticoid, glucocorticoid and androgen receptors. They exist as homodimers coupled to Hsp90 or HMGB proteins, which are shed upon activation. The major signaling pathway used by progesterone receptors is via direct DNA binding and transcriptional regulation of target genes. They can also signal by binding to other proteins, mainly with transcription factors such as NF-κB, AP-1 or STAT. Progesterone receptors are found in the female reproductive tract, mammary glands, brain and pituitary gland and receptor expression is induced by estrogen. Well established functions of progesterone receptors include ovulation, implantation, mammary gland development and maintenance of pregnancy. In addition, progesterone, signaling through the progesterone receptor, increases the ventilatory response of the respiratory centers to carbon dioxide and decreases arterial and alveolar PCO2 in the luteal phase of the menstrual cycle and during pregnancy. The human gene encoding the progesterone receptor has been localized to 11q22.
VE: 1 * 100 µG
Product Image-PRSI79-526

Anti-PGR Rabbit Polyclonal Antibody

Artikel-Nr: (PRSI79-526)
Lieferant: ProSci Inc.
Beschreibung: Progesterone receptors (PRs) are nuclear hormone receptors of the NR3C class, which also includes mineralocorticoid, glucocorticoid and androgen receptors. They exist as homodimers coupled to Hsp90 or HMGB proteins, which are shed upon activation. The major signaling pathway used by progesterone receptors is via direct DNA binding and transcriptional regulation of target genes. They can also signal by binding to other proteins, mainly with transcription factors such as NF-κB, AP-1 or STAT. Progesterone receptors are found in the female reproductive tract, mammary glands, brain and pituitary gland and receptor expression is induced by estrogen. Well established functions of progesterone receptors include ovulation, implantation, mammary gland development and maintenance of pregnancy. In addition, progesterone, signaling through the progesterone receptor, increases the ventilatory response of the respiratory centers to carbon dioxide and decreases arterial and alveolar PCO2 in the luteal phase of the menstrual cycle and during pregnancy. The human gene encoding the progesterone receptor has been localized to 11q22.
VE: 1 * 100 µG
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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