Sie suchten nach: WLD-TEC+GmbH

Lieferant: Heidolph Instruments GmbH & Co.KG

Beschreibung: Verdampfer, Rotation

Lieferant: WELLS LAMONT

Beschreibung: Sterile, wiederverwendbare und schnittfeste Unterziehhandschuhe.

Sale!

Artikel-Nr: (BOSSBS-2752R-CY7)

Lieferant: Bioss

Beschreibung: Brutons tyrosine kinase (BTK) is a member of the BTK/Tec family of cytoplasmic tyrosine kinases. Like other BTK family members, it contains a pleckstrin homology (PH) domain, Src homology SH3 and SH2 domains. BTK plays an important role in B cell development. Activation of B cells by various ligands is accompanied by BTK membrane translocation mediated by its PH domain binding to phosphatidylinositol-3,4,5-trisphosphate. The membrane located BTK is active and associated with transient phosphorylation of two tyrosine residues, Tyr551 and Tyr223. Tyr551 in the activation loop is transphosphorylated by the Src family tyrosine kinase, leading to autophosphorylation at Tyr223 within the SH3 domain, which is necessary for full activation. The activation of BTK is negatively regulated by PKC beta through phosphorylation of BTK at Ser180, which results in reduced membrane recruitment, transphosphorylation and subsequent activation. The PKC/BTK inhibitory signal is likely to be a key determinant of the B cell receptor signaling threshold to maintain optimal BTK activity.

VE: 1 * 100 µl

Sale!

Lieferant: Freudenberg Medical Europe GmbH

Beschreibung: Silikon, platinvernetzt.

Lieferant: JULABO GmbH

Beschreibung: Schüttelbad, Federklemme

Lieferant: Lenz Laborglas GmbH & CO.KG

Beschreibung: Plastik, schwarz.

Artikel-Nr: (BOSSBS-2752R-CY5)

Lieferant: Bioss

Beschreibung: Brutons tyrosine kinase (BTK) is a member of the BTK/Tec family of cytoplasmic tyrosine kinases. Like other BTK family members, it contains a pleckstrin homology (PH) domain, Src homology SH3 and SH2 domains. BTK plays an important role in B cell development. Activation of B cells by various ligands is accompanied by BTK membrane translocation mediated by its PH domain binding to phosphatidylinositol-3,4,5-trisphosphate. The membrane located BTK is active and associated with transient phosphorylation of two tyrosine residues, Tyr551 and Tyr223. Tyr551 in the activation loop is transphosphorylated by the Src family tyrosine kinase, leading to autophosphorylation at Tyr223 within the SH3 domain, which is necessary for full activation. The activation of BTK is negatively regulated by PKC beta through phosphorylation of BTK at Ser180, which results in reduced membrane recruitment, transphosphorylation and subsequent activation. The PKC/BTK inhibitory signal is likely to be a key determinant of the B cell receptor signaling threshold to maintain optimal BTK activity.

VE: 1 * 100 µl

Sale!

Artikel-Nr: (BOSSBS-2752R-CY5.5)

Lieferant: Bioss

Beschreibung: Brutons tyrosine kinase (BTK) is a member of the BTK/Tec family of cytoplasmic tyrosine kinases. Like other BTK family members, it contains a pleckstrin homology (PH) domain, Src homology SH3 and SH2 domains. BTK plays an important role in B cell development. Activation of B cells by various ligands is accompanied by BTK membrane translocation mediated by its PH domain binding to phosphatidylinositol-3,4,5-trisphosphate. The membrane located BTK is active and associated with transient phosphorylation of two tyrosine residues, Tyr551 and Tyr223. Tyr551 in the activation loop is transphosphorylated by the Src family tyrosine kinase, leading to autophosphorylation at Tyr223 within the SH3 domain, which is necessary for full activation. The activation of BTK is negatively regulated by PKC beta through phosphorylation of BTK at Ser180, which results in reduced membrane recruitment, transphosphorylation and subsequent activation. The PKC/BTK inhibitory signal is likely to be a key determinant of the B cell receptor signaling threshold to maintain optimal BTK activity.

VE: 1 * 100 µl

Sale!

Artikel-Nr: (BOSSBS-2752R-CY3)

Lieferant: Bioss

Beschreibung: Brutons tyrosine kinase (BTK) is a member of the BTK/Tec family of cytoplasmic tyrosine kinases. Like other BTK family members, it contains a pleckstrin homology (PH) domain, Src homology SH3 and SH2 domains. BTK plays an important role in B cell development. Activation of B cells by various ligands is accompanied by BTK membrane translocation mediated by its PH domain binding to phosphatidylinositol-3,4,5-trisphosphate. The membrane located BTK is active and associated with transient phosphorylation of two tyrosine residues, Tyr551 and Tyr223. Tyr551 in the activation loop is transphosphorylated by the Src family tyrosine kinase, leading to autophosphorylation at Tyr223 within the SH3 domain, which is necessary for full activation. The activation of BTK is negatively regulated by PKC beta through phosphorylation of BTK at Ser180, which results in reduced membrane recruitment, transphosphorylation and subsequent activation. The PKC/BTK inhibitory signal is likely to be a key determinant of the B cell receptor signaling threshold to maintain optimal BTK activity.

VE: 1 * 100 µl

Sale!

Lieferant: JULABO GmbH

Beschreibung: Transfer tubing, Länge: 1 m

Artikel-Nr: (THARLUEFTER)

Lieferant: THARMAC GmbH

Beschreibung: Fan

VE: 1 * 1 ST

Sale!

Artikel-Nr: (FAWE12984001)

Lieferant: FAWECO HAUTSCHUTZ

Beschreibung: O/W cream protects from oil-soluble substances such as oils, organic solvents, non-water soluble cooling lubricants, cutting oils, and other oily substances.

VE: 1 * 100 mL

Sale!

Lieferant: Heidolph Instruments GmbH & Co.KG

Beschreibung: Evaporator, rotary

Lieferant: MOTIC

Beschreibung: The Panthera TEC POL models present a high flexibility for the inspection of all kind of polarizing materials, for transparent samples like fibers and foils with their inherent birefringence, as well as for opaque specimen from education environment and industrial quality control.

Lieferant: Lenz Laborglas GmbH & CO.KG

Beschreibung: DURAN®, Borosilicate glass.

Lieferant: Heidolph Instruments GmbH & Co.KG

Beschreibung: Universaladapter