Anti-CD45 Mouse Monoclonal Antibody (PerCP) [clone: 2D1]

Lieferant: Tonbo Biosciences
67-9459-T025 67-9459-T100 67-9459-T500
67-9459-T025EA 60.8 EUR
67-9459-T025 67-9459-T100 67-9459-T500
Anti-CD45 Mouse Monoclonal Antibody (PerCP) [clone: 2D1]
Antikörper
The 2D1 antibody reacts with human CD45, one of the most abundant hematopoietic markers and one that is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, and CD45RO.

The 2D1 antibody is widely used as a marker for human CD45 expression on peripheral blood T cells, B cells, monocytes, macrophages, and NK cells.

Type: Primary
Antigen: CD45
Clonality: Monoclonal
Clone: 2D1
Conjugation: PerCP
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human
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