Anti-Bradykinin Receptor 2 Rabbit Polyclonal Antibody

Lieferant: ENZO LIFE SCIENCES
ADI905747100
ENZOADI905747100EA 470 EUR
ENZOADI905747100
Anti-Bradykinin Receptor 2 Rabbit Polyclonal Antibody
Antikörper
Bradykinin (BK) is a nine-amino acid peptide produced by kallikrein cleavage of kininogen precursor proteins in tissue and plasma, and is an important regulator of vascular and pain responses to tissue injury. Two receptors (B1 and B2) have been identified as mediators of BK signaling, and are both seven-transmembrane domain-containing GPCRs. The B2 receptor is constitutively expressed in smooth muscle and neurons, whereas B1 expression is induced following injury. B2 receptors signal via Gq alpha subunits, leading to activation of phospholipase Cbeta, hydrolysis of PI, and an intracellular increase in free calcium, although coupling through Gi, Gs, and G12/13 has also been observed.

Type: Primary
Antigen: Bradykinin receptor 2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope: near the N-Terminus
Host: Rabbit
Isotype:
Reactivity: Mouse, Rat
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