Anti-CHOP Mouse Monoclonal Antibody

Lieferant: ENZO LIFE SCIENCES
ALX804551C100
ENZOALX804551C100EA 842 EUR
ENZOALX804551C100
Anti-CHOP Mouse Monoclonal Antibody
Antikörper
CHOP is a small nuclear protein that is capable of dimerizing with transcription factors C/EBP α and β. Once dimerized, this complex inhibits the normal binding and function of C/EBP to classical binding sites. Inversely, the C/EBP-CHOP dimer gains binding activity to other non-classical C/EBP stress related targets.
Under normal cellular conditions this protein is not expressed in detectable levels, but is highly unregulated during times of cellular/ER stress. Examples of CHOP inducing stress include: treatment with tunicamycin, nutrient starvation and reducing agents that interfere with the calcium flux across the ER membrane.

  • For Immunocytochemistry, Immunoprecipitation, Western Blot

Recognizes an N-terminal epitope of human and mouse CHOP. Detects a band of ~31kDa by Western blot.

Type: Primary
Antigen: CHOP
Clonality: Monoclonal
Clone:
Conjugation:
Epitope:
Host: Mouse
Isotype:
Reactivity:
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