Anti-NAMPT Mouse Monoclonal Antibody (Biotin) [clone: OMNI379]

Lieferant: ProSci Inc.
36-035
PRSI36-035EA 567 EUR
PRSI36-035
Anti-NAMPT Mouse Monoclonal Antibody (Biotin) [clone: OMNI379]
Antikörper
Nicotinamide phosphoribosyltransferase (Nampt; pre-B cell colony-enhancing factor; PBEF; Visfatin) is an 52kDa adipokine secreted by adipose tissue and involved in the biosynthesis of nicotinamide adenine dinucleotide (NAD+). Two forms of Nampt exist, an intracellular form (iNampt) and an extracellular form (eNampt). While the function of iNampt as an essential and rate-limiting NAD+ biosynthetic enzyme is well established, the physiological role of eNampt is still a matter of debate. Nampt has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.

Type: Primary
Antigen: NAMPT
Clonality: Monoclonal
Clone: OMNI379
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG2a kappa
Reactivity: Human, Mouse, Rat
Bestellen

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Mehr About VWR