Anti-GRANULIN Rat Polyclonal Antibody

Lieferant: ProSci Inc.
36-293
PRSI36-293EA 566 EUR
PRSI36-293
Anti-GRANULIN Rat Polyclonal Antibody
Antikörper
Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. Progranulin is a biomarker for FTLD, other types of Alzheimer‘s Disease (AD) and potentially for MCI (Mild Cognitive Impairment). Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.

Type: Primary
Antigen: GRANULIN
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rat
Isotype:
Reactivity: Mouse
Bestellen

Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Mehr About VWR