Anti-CD22 Mouse Monoclonal Antibody [clone: HIB22] (PE)

Lieferant: STEMCELL Technologies
60083PE
STMC60083PEEA 0 EUR
STMC60083PE
Anti-CD22 Mouse Monoclonal Antibody [clone: HIB22] (PE)
Antikörper
Mouse monoclonal IgG1 antibody against human, chimpanzee CD22, PE­conjugated.

  • B cells

The HIB22 antibody reacts with CD22 (Siglec-2), a type I transmembrane glycoprotein expressed in the cytoplasm of pro-B and pre-B cells and on the surface of mature and activated B cells and B cell lymphomas, but not on plasma cells. CD22 functions as an inhibitory receptor for B cell receptor signaling and plays roles in modulating the activation threshold of B cells and controlling CD40 signaling. CD22 comprises two isoforms generated by alternative splicing: CD22αMore Product Information
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