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Image Unavailable-BNC470511-500

Anti-CD7 Mouse Monoclonal Antibody (CF647) [clone: C7/511]

Lieferant: Biotium
Beschreibung: Recognizes a protein of 40 kDa, identified as CD7, a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.

Image Unavailable-BNC880978-100

Anti-CD7 Mouse Monoclonal Antibody (CF488A) [clone: T3-3A1]

Lieferant: Biotium
Beschreibung: Recognizes a protein of 40 kDa, identified as CD7, a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.

Image Unavailable-BOSSBS-5805R-CY7

Anti-DSTYK Rabbit Polyclonal Antibody (Cy7®)

Artikel-Nr: (BOSSBS-5805R-CY7)
Lieferant: Bioss
Beschreibung: Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage. Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor. Phosphorylates DAB2IP at 'Ser-728' in a TNF-alpha-dependent manner, and thereby activates the MAP3K5-JNK apoptotic cascade. Ubiquitination by TRAF2 via 'Lys-63'-link chains acts as a critical enhancer of communication with downstream signal transducers in the mitogen-activated protein kinase pathway and the NF-kappa-B pathway, which in turn mediate downstream events including the activation of genes encoding inflammatory molecules. Polyubiquitinated protein binds to IKBKG/NEMO, the regulatory subunit of the IKK complex, a critical event for NF-kappa-B activation. Interaction with other cellular RHIM-containing adapters initiates gene activation and cell death. RIPK1 and RIPK3 association, in particular, forms a necrosis-inducing complex.
VE: 1 * 100 µl
Image Unavailable-BNC680310-500

Anti-CD7 Mouse Monoclonal Antibody (CF568) [clone: B-F12]

Lieferant: Biotium
Beschreibung: Recognizes a protein of 40 kDa, identified as CD7 (also known as gp40, Leu9). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.

Image Unavailable-BOSSBS-5164R-CY5

Anti-ETS1 associated Protein II Rabbit Polyclonal Antibody (Cy5®)

Artikel-Nr: (BOSSBS-5164R-CY5)
Lieferant: Bioss
Beschreibung: DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.
VE: 1 * 100 µl
Image Unavailable-BOSSBS-5164R

Anti-ETS1 associated protein II Rabbit Polyclonal Antibody

Artikel-Nr: (BOSSBS-5164R)
Lieferant: Bioss
Beschreibung: DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. Hydrolyzes 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.
VE: 1 * 100 µl
Image Unavailable-BNC401046-500

Anti-CD7 Mouse Monoclonal Antibody (CF640R) [clone: 124.1D1]

Lieferant: Biotium
Beschreibung: Recognizes a protein of 40 kDa, identified as CD7 (Workshop IV; Code T155). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.

Image Unavailable-181-0314

Accessories for VWR® Diaphragm Pump

Lieferant: VWR Collection
Beschreibung: Dampf-Rückgewinnungskit für Pumpe und Manometer VP 220, ermöglicht eine effiziente Rückgewinnung von Lösungsmitteln und den effizienten Schutz von Laborumgebung und Manometer

Product Image-1.14693.0001

Spectroquant® PhotoCheck, Supelco®

Artikel-Nr: (1.14693.0001)
Lieferant: Merck
Beschreibung: Der PhotoCheck ist für den Test der Wellenlängenrichtigkeit von allen Merck Photometern konzipiert und kann als sekundärer Standard für Testinstrumente gemäß DIN/ISO 9000 und ISO 14000 verwendet werden. Die stabilen Farblösungen dienen der Überprüfung folgender Filter bzw. Wellenlängeneinstellungen in Spektralphotometern: 445 und 446 nm, 520 und 525 nm und 690 nm. Die richtige Wellenlängeneinstellung und die Linearität der Extinktionsmessung wird mit vier Lösungen pro Wellenlänge geprüft. Die Rückverfolgbarkeit dieser Prüflösungen auf internationale Standards wird durch Überprüfung in einem Referenz-Spektralphotometer garantiert, der mit dem Primärstandard (NIST) verglichen wird. Diese Werte sind dokumentiert und werden als Teil des Sets geliefert.
VE: 1 * 1 SET

Sicherheitsdatenblätter Zertifikate


Image Unavailable-BOSSBS-10055R-FITC

Anti-DSTYK Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Artikel-Nr: (BOSSBS-10055R-FITC)
Lieferant: Bioss
Beschreibung: Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage. Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor. Phosphorylates DAB2IP at 'Ser-728' in a TNF-alpha-dependent manner, and thereby activates the MAP3K5-JNK apoptotic cascade. Ubiquitination by TRAF2 via 'Lys-63'-link chains acts as a critical enhancer of communication with downstream signal transducers in the mitogen-activated protein kinase pathway and the NF-kappa-B pathway, which in turn mediate downstream events including the activation of genes encoding inflammatory molecules. Polyubiquitinated protein binds to IKBKG/NEMO, the regulatory subunit of the IKK complex, a critical event for NF-kappa-B activation. Interaction with other cellular RHIM-containing adapters initiates gene activation and cell death. RIPK1 and RIPK3 association, in particular, forms a necrosis-inducing complex.
VE: 1 * 100 µl
Image Unavailable-BOSSBS-5805R-A680

Anti-RIPK-1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-5805R-A680)
Lieferant: Bioss
Beschreibung: Serine-threonine kinase which transduces inflammatory and cell-death signals (programmed necrosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage. Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor. Phosphorylates DAB2IP at 'Ser-728' in a TNF-alpha-dependent manner, and thereby activates the MAP3K5-JNK apoptotic cascade. Ubiquitination by TRAF2 via 'Lys-63'-link chains acts as a critical enhancer of communication with downstream signal transducers in the mitogen-activated protein kinase pathway and the NF-kappa-B pathway, which in turn mediate downstream events including the activation of genes encoding inflammatory molecules. Polyubiquitinated protein binds to IKBKG/NEMO, the regulatory subunit of the IKK complex, a critical event for NF-kappa-B activation. Interaction with other cellular RHIM-containing adapters initiates gene activation and cell death. RIPK1 and RIPK3 association, in particular, forms a necrosis-inducing complex.
VE: 1 * 100 µl
Product Image-87814.290

Fehling-Reagenz (Kit, enthält Lösung I und II) Reag. Ph. Eur. 1023300 für die qualitative Bestimmung von reduzierenden Zuckern

Artikel-Nr: (87814.290)
Lieferant: VWR Chemicals
Beschreibung: Fehling-Reagenz (Kit, enthält Lösung I und II) Reag. Ph. Eur. 1023300 für die qualitative Bestimmung von reduzierenden Zuckern
VE: 1 * 1 KIT

Sicherheitsdatenblätter Zertifikate


Product Image-31701.296

Fehling-Reagenz (Kit, enthält Lösung I und II) für die qualitative Bestimmung von reduzierenden Zuckern

Artikel-Nr: (31701.296)
Lieferant: VWR Chemicals
Beschreibung: 10 ml Lösung entspricht ca. 0,050 g wasserfreier Glucose
VE: 1 * 1 L

Sicherheitsdatenblätter Zertifikate


Image Unavailable-BNUM0310-50

Anti-CD7 Mouse Monoclonal Antibody (Purified, BSA-free) [clone: B-F12]

Artikel-Nr: (BNUM0310-50)
Lieferant: Biotium
Beschreibung: Recognizes a protein of 40 kDa, identified as CD7 (also known as gp40, Leu9). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.
VE: 1 * 50 µl
Image Unavailable-BOSSBS-5164R-A680

Anti-ETS1 associated protein 2 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Artikel-Nr: (BOSSBS-5164R-A680)
Lieferant: Bioss
Beschreibung: DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 5'-phosphodiester bond, giving rise to DNA with a free 5' phosphate. catalyses the hydrolysis of dead-end complexes between DNA and the topoisomerase 2 (TOP2) active site tyrosine residue. hydrolyses 5'-phosphoglycolates on protruding 5' ends on DNA double-strand breaks (DSBs) due to DNA damage by radiation and free radicals. The 5'-tyrosyl DNA phosphodiesterase activity can enable the repair of TOP2-induced DSBs without the need for nuclease activity, creating a 'clean' DSB with 5'-phosphate termini that are ready for ligation. Has also 3'-tyrosyl DNA phosphodiesterase activity, but less efficiently and much slower than TDP1. May also act as a negative regulator of ETS1 and may inhibit nuclear factor-kappa-B activation.
VE: 1 * 100 µl
Image Unavailable-SHH0021-1KT

Melanin Bleichkit

Artikel-Nr: (SHH0021-1KT)
Lieferant: SIGMA ALDRICH MICROSCOPY
Beschreibung: Ein einfach zu verwendendes Zwei-Schritte-Kit, das Melanin reduziert und gleichzeitig empfindliches Gewebe, zytologische Details und Antigene bewahrt. Schwere Melaninpigmente in den Zellen können die Zellmorphologie verschleiern und anschließend die Interpretation bei Verwendung routinemäßiger oder spezieller histochemischer Färbungen beeinträchtigen. Das Melanin-Bleichkit ermöglicht die Entfernung von Melanin aus Gewebeschnitten, sodass positive Färbungen richtig interpretiert werden können. Ein Zwei-Schritt-Kit, das kein Mischen erfordert. Wird vor der Färbung verwendet, um Melanin zu reduzieren und gleichzeitig empfindliches Gewebe, zytologische Details und Antigene zu bewahren.
VE: 1 * 1 KIT
Preis auf Anfrage
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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
Dieses Produkt kann nur an eine Lieferadresse versandt werden die über die entsprechende Lizenzen verfügt. Für weitere Hilfe bitte kontaktieren Sie Ihr VWR Vertriebszentrum.
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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