Sie suchten nach: Bioss

Artikel-Nr: (BOSSBS-9365R)

Lieferant: Bioss

Beschreibung: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Necessary for activation of the CDC28 kinase.

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Artikel-Nr: (BOSSBS-0625R)

Lieferant: Bioss

Beschreibung: Anti-ZNF268 Rabbit Polyclonal Antibody

VE: 1 * 100 µl

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Artikel-Nr: (BOSSBS-0699R)

Lieferant: Bioss

Beschreibung: Probable acetyl-CoA transporter necessary for O-acetylation of gangliosides (PubMed:9096318). Negatively regulates BMP signaling (PubMed:25402622).

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Artikel-Nr: (BOSSBS-0716R)

Lieferant: Bioss

Beschreibung: Activates apoptosis.

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Artikel-Nr: (BOSSBS-13000R)

Lieferant: Bioss

Beschreibung: This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function. [provided by RefSeq, Jul 2008].

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Artikel-Nr: (BOSSBS-13003R)

Lieferant: Bioss

Beschreibung: DIRAS2 belongs to a distinct branch of the functionally diverse Ras (see HRAS; MIM 190020) superfamily of monomeric GTPases.[supplied by OMIM, Apr 2004].

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Artikel-Nr: (BOSSBS-11023R)

Lieferant: Bioss

Beschreibung: Anti-DNAH7 Rabbit Polyclonal Antibody

VE: 1 * 100 µl

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Artikel-Nr: (BOSSBS-11028R)

Lieferant: Bioss

Beschreibung: Facilitates tyrosination of alpha-tubulin in neuronal microtubules (By similarity). Phosphorylated MAP1B may play a role in the cytoskeletal changes that accompany neurite extension. Possibly MAP1B binds to at least two tubulin subunits in the polymer, and this bridging of subunits might be involved in nucleating microtubule polymerization and in stabilizing microtubules. Acts as a positive cofactor in DAPK1-mediated autophagic vesicle formation and membrane blebbing.

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Artikel-Nr: (BOSSBS-11035R)

Lieferant: Bioss

Beschreibung: Anti-TNFAIP8L2 Rabbit Polyclonal Antibody

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Artikel-Nr: (BOSSBS-11014R)

Lieferant: Bioss

Beschreibung: ILVBL is a 632 amino acid single-pass membrane protein that belongs to the TPP enzyme family. Expressed in the majority of tissues, ILVBL has the highest level of expression in heart, pancreas and placenta. ILVBL is highly homologous to several bacterial enzymes, including the B isozyme of the large catalytic subunit of E. coli acetohydroxy-acid synthase (AHAS) and the oxalyl-coA decarboxylase of O. formigenes, that utilize thiamine pyrophosphate as a cofactor. ILVBL binds one magnesium ion and one thiamine pyrophosphate per subunit, and may catalyze the initial step in branched-chain amino acid biosynthesis. The gene encoding ILVBL maps to human chromosome 19p13.12 and mouse chromosome 10 C1.

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Artikel-Nr: (BOSSBS-11020R)

Lieferant: Bioss

Beschreibung: Actin filament associated protein (AFAP-110) interacts directly with actin filaments through its C-terminal actin-binding domain. AFAP-110 contains additional protein-binding domains as well, and serves as an adaptor protein. By linking signaling molecules to actin filaments, AFAP-110 provides a platform for the preparation of larger signaling complexes, activates Src kinases in response to cellular signals and also directly affects Actin organization as an Actin filament cross-linking protein. AFAP-1L2 (Actin filament-associated protein 1-like 2), also known as XB130, is a 818 amino acid cytoplasmic protein that contains two Pleckstrin homology (PH) domains, which are normally found in proteins involved in intracellular signaling. Like its relative AFAP110, AFAP-1L2 interacts with Src kinase and may play a role in Src-regulated transcription activation. AFAP-1L2 is expressed in thyroid and spleen and can also be detected at lower levels in lung, brain, pancreas and kidney. There are four isoforms of AFAP-1L2 that are produced as a result of alternative splicing events.

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Artikel-Nr: (BOSSBS-3932R)

Lieferant: Bioss

Beschreibung: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA).

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Artikel-Nr: (BOSSBS-13557R)

Lieferant: Bioss

Beschreibung: Anti-ZBT24/ZNF45 Rabbit Polyclonal Antibody

VE: 1 * 100 µl

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Artikel-Nr: (BOSSBS-13541R)

Lieferant: Bioss

Beschreibung: Trace amines are endogenous molecules structurally related to classical biogenic amines that are linked to psychiatric conditions. A family of G-protein coupled receptors referred to as trace-amine-associated receptors (TAAR) are activated by trace amines and are present in very low levels in mammalian tissue. TAAR’s contain several structural features that are similar to the rhodopsin beta-adrenergic receptor superfamily, including the positions of the seven transmembrane regions that provide common ligand-binding pockets as well as the short N- and C-terminal domains. TAAR proteins are potential targets for drugs of abuse, such as amphetamine and MDMA, as well as neuropsychiatric disorders including schizophrenia, depression, and attention deficit disorder. TAAR-1 is a 340 amino acid protein that increases intracellular cAMP accumulation in response to beta-phenylethylamine and tyramine. TAAR-1 is associated with the detection of social cues, illustrating its significance as a therapeutic target.

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Artikel-Nr: (BOSSBS-13554R)

Lieferant: Bioss

Beschreibung: Anti-ZBED4 Rabbit Polyclonal Antibody

VE: 1 * 100 µl

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Artikel-Nr: (BOSSBS-10110R)

Lieferant: Bioss

Beschreibung: Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.

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