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Artikel-Nr: (BOSSBS-8687R-CY7)
Lieferant: Bioss
Beschreibung: p53, a DNA-binding, oligomerization domain- and transcription activation domain-containing tumor suppressor, upregulates growth arrest and apoptosis-related genes in response to stress signals, thereby influencing programmed cell death, cell differentiation, and cell cycle control mechanisms. p53 localizes to the nucleus, yet can be chaperoned to the cytoplasm by the negative regulator, MDM2. MDM2 is an E3 ubiquitin ligase that is upregulated in the presence of active p53, where it poly-ubiquitinates p53 for proteasome targeting. p53 fluctuates between latent and active DNA-binding conformations and is differentially activated through posttranslational modifications, including phosphorylation and acetylation. Mutations in the DNA-binding domain (DBD) of p53, amino acids 110-286, can compromise energetically-favorable association with cis elements and are implicated in several human cancers.
VE: 1 * 100 µl


Artikel-Nr: (BOSSBS-8687R-CY5)
Lieferant: Bioss
Beschreibung: p53, a DNA-binding, oligomerization domain- and transcription activation domain-containing tumor suppressor, upregulates growth arrest and apoptosis-related genes in response to stress signals, thereby influencing programmed cell death, cell differentiation, and cell cycle control mechanisms. p53 localizes to the nucleus, yet can be chaperoned to the cytoplasm by the negative regulator, MDM2. MDM2 is an E3 ubiquitin ligase that is upregulated in the presence of active p53, where it poly-ubiquitinates p53 for proteasome targeting. p53 fluctuates between latent and active DNA-binding conformations and is differentially activated through posttranslational modifications, including phosphorylation and acetylation. Mutations in the DNA-binding domain (DBD) of p53, amino acids 110-286, can compromise energetically-favorable association with cis elements and are implicated in several human cancers.
VE: 1 * 100 µl


Artikel-Nr: (BOSSBS-8687R-CY3)
Lieferant: Bioss
Beschreibung: p53, a DNA-binding, oligomerization domain- and transcription activation domain-containing tumor suppressor, upregulates growth arrest and apoptosis-related genes in response to stress signals, thereby influencing programmed cell death, cell differentiation, and cell cycle control mechanisms. p53 localizes to the nucleus, yet can be chaperoned to the cytoplasm by the negative regulator, MDM2. MDM2 is an E3 ubiquitin ligase that is upregulated in the presence of active p53, where it poly-ubiquitinates p53 for proteasome targeting. p53 fluctuates between latent and active DNA-binding conformations and is differentially activated through posttranslational modifications, including phosphorylation and acetylation. Mutations in the DNA-binding domain (DBD) of p53, amino acids 110-286, can compromise energetically-favorable association with cis elements and are implicated in several human cancers.
VE: 1 * 100 µl


Artikel-Nr: (BOSSBS-8687R-HRP)
Lieferant: Bioss
Beschreibung: p53, a DNA-binding, oligomerization domain- and transcription activation domain-containing tumor suppressor, upregulates growth arrest and apoptosis-related genes in response to stress signals, thereby influencing programmed cell death, cell differentiation, and cell cycle control mechanisms. p53 localizes to the nucleus, yet can be chaperoned to the cytoplasm by the negative regulator, MDM2. MDM2 is an E3 ubiquitin ligase that is upregulated in the presence of active p53, where it poly-ubiquitinates p53 for proteasome targeting. p53 fluctuates between latent and active DNA-binding conformations and is differentially activated through posttranslational modifications, including phosphorylation and acetylation. Mutations in the DNA-binding domain (DBD) of p53, amino acids 110-286, can compromise energetically-favorable association with cis elements and are implicated in several human cancers.
VE: 1 * 100 µl


Artikel-Nr: (BOSSBS-8687R-A680)
Lieferant: Bioss
Beschreibung: p53, a DNA-binding, oligomerisation domain- and transcription activation domain-containing tumor suppressor, upregulates growth arrest and apoptosis-related genes in response to stress signals, thereby influencing programmed cell death, cell differentiation, and cell cycle control mechanisms. p53 localises to the nucleus, yet can be chaperoned to the cytoplasm by the negative regulator, MDM2. MDM2 is an E3 ubiquitin ligase that is upregulated in the presence of active p53, where it poly-ubiquitinates p53 for proteasome targeting. p53 fluctuates between latent and active DNA-binding conformations and is differentially activated through posttranslational modifications, including phosphorylation and acetylation. Mutations in the DNA-binding domain (DBD) of p53, amino acids 110-286, can compromise energetically-favorable association with cis elements and are implicated in several human cancers.
VE: 1 * 100 µl


Artikel-Nr: (BOSSBS-8687R-A647)
Lieferant: Bioss
Beschreibung: p53, a DNA-binding, oligomerization domain- and transcription activation domain-containing tumor suppressor, upregulates growth arrest and apoptosis-related genes in response to stress signals, thereby influencing programmed cell death, cell differentiation, and cell cycle control mechanisms. p53 localizes to the nucleus, yet can be chaperoned to the cytoplasm by the negative regulator, MDM2. MDM2 is an E3 ubiquitin ligase that is upregulated in the presence of active p53, where it poly-ubiquitinates p53 for proteasome targeting. p53 fluctuates between latent and active DNA-binding conformations and is differentially activated through posttranslational modifications, including phosphorylation and acetylation. Mutations in the DNA-binding domain (DBD) of p53, amino acids 110-286, can compromise energetically-favorable association with cis elements and are implicated in several human cancers.
VE: 1 * 100 µl


Artikel-Nr: (BOSSBS-8687R-FITC)
Lieferant: Bioss
Beschreibung: p53, a DNA-binding, oligomerization domain- and transcription activation domain-containing tumor suppressor, upregulates growth arrest and apoptosis-related genes in response to stress signals, thereby influencing programmed cell death, cell differentiation, and cell cycle control mechanisms. p53 localizes to the nucleus, yet can be chaperoned to the cytoplasm by the negative regulator, MDM2. MDM2 is an E3 ubiquitin ligase that is upregulated in the presence of active p53, where it poly-ubiquitinates p53 for proteasome targeting. p53 fluctuates between latent and active DNA-binding conformations and is differentially activated through posttranslational modifications, including phosphorylation and acetylation. Mutations in the DNA-binding domain (DBD) of p53, amino acids 110-286, can compromise energetically-favorable association with cis elements and are implicated in several human cancers.
VE: 1 * 100 µl


Lieferant: ZEISS
Beschreibung: Accessory for microscopes, Axio Vert, Für: A1 FL-LED, Reflektormodul FL EG P&C

Artikel-Nr: (HAAK808-0579)
Lieferant: HAAKE
Beschreibung: Zubehör für Viskosimeter, Joint clutch for E, FL and RS sensors, Für: 550
VE: 1 * 1 ST


Lieferant: VARIAN
Beschreibung: Bondesil™ FL bulk sorbent, 200 µm

Artikel-Nr: (ANTIA319473-96)
Lieferant: ANTIBODIES.COM
Beschreibung: Das Maus Adenovirus (FL-Stamm)-ELISA-Kit ist ein Sandwich-Enzyme-Linked Immunosorbent Assay (sELISA) zur quantitativen <em>in vitro</em> Bestimmung von Maus Adenovirus (FL Stamm) Serum, Plasma, Gewebehomogenaten und anderen biologischen Flüssigkeiten.
VE: 1 * 96 Tests

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Lieferant: PerkinElmer
Beschreibung: Supra-Clean® Florisil (FL-S) SPE-Produkte werden für die Extraktion polarer Verbindungen bei der Analyse von Pestiziden und polychlorierten Biphenylen (PCB) empfohlen.

Lieferant: MOTIC
Beschreibung: Accessory for microscopes, CCIS® Plan FLUOR Objektiv UC PL FL 40X/0,75/S (WD=0,7mm)

Lieferant: PerkinElmer
Beschreibung: Supra-Clean® Florisil (FL-S) SPE-Säulen für Pestizide werden bei der Analyse von Pestiziden für die Extraktion polarer Verbindungen empfohlen.

Lieferant: AAT BIOQUEST
Beschreibung: ReadiView™ Green/Red Viability stain is a robust cell stain optimised for staining nucleated cells in Countess II FL or Countess 3 FL instruments.

Lieferant: LEICA MICROSYSTEMS
Beschreibung: Die Objektivlinse ist ein kritischer Teil der Mikroskopoptik. Das Mikroskopobjektiv wird in der Nähe der zu beobachtenden Probe, Probe oder des Objekts positioniert. Es spielt eine sehr wichtige Rolle bei der Bildgebung, da es das erste vergrößerte Bild der Probe erzeugt.

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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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