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Artikel-Nr: (AATB2116)
Lieferant: AAT BIOQUEST INC
Beschreibung: Tide Quencher™ 7.1 (TQ7.1) is a non-fluorescent molecule designed to efficiently quench the fluorescence of common NIR fluorophores such as Cy7, Alexa Fluor® 700, Alexa Fluor® 750, iFluor® 700, iFluor® 710, iFluor® 720 and iFluor® 750.
VE: 1 * 100 mg

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Artikel-Nr: (AATB2117)
Lieferant: AAT BIOQUEST INC
Beschreibung: Tide Quencher™ 7.1 (TQ7.1) is a non-fluorescent molecule designed to efficiently quench the fluorescence of common NIR fluorophores such as Cy7, Alexa Fluor® 700, Alexa Fluor® 750, iFluor® 700, iFluor® 710, iFluor® 720 and iFluor® 750.
VE: 1 * 100 mg

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Artikel-Nr: (PRSI25-590)
Lieferant: ProSci Inc.
Beschreibung: DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). However, unlike the other family members, MBD3 is not capable of binding to methylated DNA. The predicted MBD3 protein shares 71% and 94% identity with MBD2 (isoform 1) and mouse Mbd3. MBD3 is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. MBD3 mediates the association of metastasis-associated protein 2 (MTA2) with the core histone deacetylase complex.DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). However, unlike the other family members, MBD3 is not capable of binding to methylated DNA. The predicted MBD3 protein shares 71% and 94% identity with MBD2 (isoform 1) and mouse Mbd3. MBD3 is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. MBD3 mediates the association of metastasis-associated protein 2 (MTA2) with the core histone deacetylase complex. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
VE: 1 * 50 µG


Lieferant: SGE Analytical Science
Beschreibung: Autosampler-Spritzen für HP7673, 7683, 7693A und 6850ALS.

Artikel-Nr: (APOSBIMN2051-1G)
Lieferant: Apollo Scientific
Beschreibung: FAM-CPG
VE: 1 * 1 g


Artikel-Nr: (ENZOALX746056M001)
Lieferant: ENZO LIFE SCIENCES
Beschreibung: CpG oligodeoxynucleotide (Type B) with phosphorothioate backbone. Specific ligand for human and mouse TLR9 (Toll-like receptor 9).
VE: 1 * 1 mg

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Artikel-Nr: (USBI038232-BIOTIN)
Lieferant: US Biological
Beschreibung: Anti-MBD2 Rabbit Polyclonal Antibody (Biotin)
VE: 1 * 200 µl


Artikel-Nr: (USBI038241-BIOTIN)
Lieferant: US Biological
Beschreibung: Anti-MBD4 Rabbit Polyclonal Antibody (Biotin)
VE: 1 * 200 µl


Artikel-Nr: (H62838.MD)
Lieferant: Thermo Scientific
Beschreibung: N-Boc-2-cyclopentyl-L-glycine dicyclohexylammonium salt 95%
VE: 1 * 250 mg

Zertifikate


Artikel-Nr: (USBI038309-FITC)
Lieferant: US Biological
Beschreibung: Anti-MECP2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
VE: 1 * 200 µl


Artikel-Nr: (BOSSBS-13025R-A555)
Lieferant: Bioss
Beschreibung: Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome. DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines residing in the dinucleotide CpG motif, and this methylation results in transcriptional repression of the target gene. The Dnmt enzymes are encoded by independent genes. Dnmt1 is the most abundant, and it preferentially methylates hemimethylated DNA and coordinates gene expression during development. Additional mammalian Dnmt proteins include Dnmt2 and Dnmt3. Dnmt2 lacks the large N-terminal regulator domain of Dnmt1, is expressed at substantially lower levels in adult tissues, and is likely involved in methylating newly integrated retroviral DNA. Dnmt3a and Dnmt3b are encoded by two distinct genes, but both are abundantly expressed in embryonic stem cells, where they also methylate CpG motifs on DNA.
VE: 1 * 100 µl


Artikel-Nr: (BOSSBS-13025R-A647)
Lieferant: Bioss
Beschreibung: Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome. DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines residing in the dinucleotide CpG motif, and this methylation results in transcriptional repression of the target gene. The Dnmt enzymes are encoded by independent genes. Dnmt1 is the most abundant, and it preferentially methylates hemimethylated DNA and coordinates gene expression during development. Additional mammalian Dnmt proteins include Dnmt2 and Dnmt3. Dnmt2 lacks the large N-terminal regulator domain of Dnmt1, is expressed at substantially lower levels in adult tissues, and is likely involved in methylating newly integrated retroviral DNA. Dnmt3a and Dnmt3b are encoded by two distinct genes, but both are abundantly expressed in embryonic stem cells, where they also methylate CpG motifs on DNA.
VE: 1 * 100 µl


Artikel-Nr: (USBI038240-APC)
Lieferant: US Biological
Beschreibung: Anti-MBD4 Rabbit Polyclonal Antibody (APC (Allophycocyanin))
VE: 1 * 200 µl


Artikel-Nr: (USBIM2472-03B)
Lieferant: US Biological
Beschreibung: Anti-MBD2 Goat Polyclonal Antibody
VE: 1 * 100 µG


Artikel-Nr: (BOSSBS-13025R-FITC)
Lieferant: Bioss
Beschreibung: Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome. DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines residing in the dinucleotide CpG motif, and this methylation results in transcriptional repression of the target gene. The Dnmt enzymes are encoded by independent genes. Dnmt1 is the most abundant, and it preferentially methylates hemimethylated DNA and coordinates gene expression during development. Additional mammalian Dnmt proteins include Dnmt2 and Dnmt3. Dnmt2 lacks the large N-terminal regulator domain of Dnmt1, is expressed at substantially lower levels in adult tissues, and is likely involved in methylating newly integrated retroviral DNA. Dnmt3a and Dnmt3b are encoded by two distinct genes, but both are abundantly expressed in embryonic stem cells, where they also methylate CpG motifs on DNA.
VE: 1 * 100 µl


Artikel-Nr: (BOSSBS-13025R-CY5)
Lieferant: Bioss
Beschreibung: Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome. DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines residing in the dinucleotide CpG motif, and this methylation results in transcriptional repression of the target gene. The Dnmt enzymes are encoded by independent genes. Dnmt1 is the most abundant, and it preferentially methylates hemimethylated DNA and coordinates gene expression during development. Additional mammalian Dnmt proteins include Dnmt2 and Dnmt3. Dnmt2 lacks the large N-terminal regulator domain of Dnmt1, is expressed at substantially lower levels in adult tissues, and is likely involved in methylating newly integrated retroviral DNA. Dnmt3a and Dnmt3b are encoded by two distinct genes, but both are abundantly expressed in embryonic stem cells, where they also methylate CpG motifs on DNA.
VE: 1 * 100 µl


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Lager für diesen Artikel ist begrenzt, kann aber in einem Lagerhaus in Ihrer Nähe zur Verfügung. Bitte stellen Sie sicher, dass Sie in sind angemeldet auf dieser Seite, so dass verfügbare Bestand angezeigt werden können. Wenn das call noch angezeigt wird und Sie Hilfe benötigen, rufen Sie uns an 1-800-932 - 5000.
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