Sie suchten nach: 8-Bromoadenosine+3\',5\'-cyclic+Monophosphothioate,+Rp-Isomer+sod

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Inhibitor of cAMP-dependent protein kinase (PKA), preferentially binding to type I PKA. Lipophilic analog of Rp-cAMPS. Resistant to mammalian cyclic nucleotide-dependent phosphodiesterases. Significantly more lipophilic and membrane permeant as compared to Rp-cAMPS or 8-Br-cAMP.

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Artikel-Nr: (ENZOALX480025M001)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: PKA activator.

VE: 1 * 1 mg

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Lieferant: ENZO LIFE SCIENCES

Beschreibung: Potent selective inhibitor of cGMP-dependent protein kinase 1α, 1β and type II. Resistant to mammalian cyclic nucleotide-dependent phosphodiesterases, no metabolic side effects. Significantly more lipophilic and membrane permeant as compared to Rp-cGMPS or Rp-8-Br-cGMPS.

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Artikel-Nr: (ENZOALX480072M001)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Inhibitor of cGMP-dependent protein kinase (PKG) 1α (cGMP antagonist). Resistant against mammalian cyclic nucleotid-dependent phosphodiesterases. No metabolic side effects. Low membrane permeability.

VE: 1 * 1 mg

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Artikel-Nr: (ENZOALX480085M001)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Competitive inhibitor of cyclic AMP-dependent protein kinase I and II.Metabolic stability towards mammalian cyclic nucleotide- responsive phosphodiesterases.
Discriminates between protein kinase A (antagonist) and some other cyclic AMP receptors, e.g. channels or CAP 3 (agonist).Membrane-permeant for several systems (for improved permeability more lipophilic analogues e.g. Rp-8-Br-cAMPS are recommended).

VE: 1 * 1 mg

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Artikel-Nr: (ENZOBMLCN2060001)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: A cell-permeable cGMP antagonist which is resistant to hydrolysis by cyclic nucleotide phosphodiesterases (Ki=0.5 µM). No metabolic side effects. Significantly more lipophilic and membrane permeant as compared to Rp-cGMPS or Rp-8-Br-cGMPS

VE: 1 * 1 mg

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Lieferant: ENZO LIFE SCIENCES

Beschreibung: PKA activator.

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Artikel-Nr: (ENZOBMLCN1350001)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Rp-cAMPS is a potent and specific competitive inhibitor of the activation of cAMP-dependent protein kinases by cAMP (IC50=4.9 µM) . Its cell permeability and complete resistance to cyclic nucleotide phosphodiesterases make it a unique tool for studying cAMP-dependent signaling. Significantly more lipophilc as compared to cAMP and thus membrane permeable in many biological systems. This product is not sterile.

VE: 1 * 1 mg

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Lieferant: Apollo Scientific

Beschreibung: 4-Methyl-1,3,2-dioxathiolan-2-oxid (Gemisch von Isomeren) 98%

Artikel-Nr: (ENZOBMLCN2160500)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Cell-permeable, phosphodiesterase-resistant cGMP antagonist. Reversed NO stimulation of random migration in rabbit neutrophils. Used at 30µM to cometively inhibit 8-Br-cGMP relaxation of rabbit aortas. The product is not sterile. Resistant to nucleotide-dependent phosphodiesterases; no metabolic side effects. Significantly more lipophilic and membrane permeant as compared to cyclic GMP or Rp-cGMPS.

VE: 1 * 500 µG

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Lieferant: Merck

Beschreibung: Purospher® STAR RP-8 endcapped basiert auf hochreinem Kieselgel und einer nahezu kompletten Oberflächenabdeckung. Die Purospher® STAR RP-8 bietet somit eine ausgezeichnete Peak-Symmetrie für saure, basische und sogar chelatbildende Verbindungen, höchste Säuleneffizienz in Bezug auf die Anzahl der theoretischen Böden, und eine außergewöhnliche Stabilität von pH 1,5 bis 10,5. Darüber hinaus bieten Purospher® STAR RP-8 endcapped-Säulen einen breiten Anwendungsbereich. Da das Sorbens weniger hydrophob als das der Purospher® STAR RP-18 endcapped ist, eluieren Analyten in der Regel schneller auf der C8-Phase. Purospher® STAR RP-8 endcapped bietet verbesserte Selektivität für positionelle Isomere und symmetrische Peakformen für stark basische und weniger hydrophobe Verbindungen.

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Artikel-Nr: (BOSSBS-11332R-A488)

Lieferant: Bioss

Beschreibung: Glutamic acid rich protein (GARP) is a soluble protein localized to the outer segments of the rod photoreceptor. It forms a subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. There are 3 isoforms produced by alternative splicing. Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties; it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit. Defects in GARP are the cause of retinitis pigmentosa type 25 (RP25). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.

VE: 1 * 100 µl

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Artikel-Nr: (BOSSBS-11332R-CY7)

Lieferant: Bioss

Beschreibung: Glutamic acid rich protein (GARP) is a soluble protein localized to the outer segments of the rod photoreceptor. It forms a subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. There are 3 isoforms produced by alternative splicing. Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties; it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit. Defects in GARP are the cause of retinitis pigmentosa type 25 (RP25). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.

VE: 1 * 100 µl

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Artikel-Nr: (BOSSBS-11332R-CY5)

Lieferant: Bioss

Beschreibung: Glutamic acid rich protein (GARP) is a soluble protein localized to the outer segments of the rod photoreceptor. It forms a subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. There are 3 isoforms produced by alternative splicing. Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties; it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit. Defects in GARP are the cause of retinitis pigmentosa type 25 (RP25). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.

VE: 1 * 100 µl

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Artikel-Nr: (BOSSBS-11332R-A350)

Lieferant: Bioss

Beschreibung: Glutamic acid rich protein (GARP) is a soluble protein localized to the outer segments of the rod photoreceptor. It forms a subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. There are 3 isoforms produced by alternative splicing. Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties; it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit. Defects in GARP are the cause of retinitis pigmentosa type 25 (RP25). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.

VE: 1 * 100 µl

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Artikel-Nr: (BOSSBS-11332R-HRP)

Lieferant: Bioss

Beschreibung: Glutamic acid rich protein (GARP) is a soluble protein localized to the outer segments of the rod photoreceptor. It forms a subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. There are 3 isoforms produced by alternative splicing. Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties; it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit. Defects in GARP are the cause of retinitis pigmentosa type 25 (RP25). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.

VE: 1 * 100 µl

Sale!