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Bongkrekic acid triammonium salt ≥92% (durch HPLC)

Artikel-Nr: (ENZOBMLCM1131000)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Bongkrekic acid is an inhibitory ligand of the mitochondrial adenine nucleotide translocase. It inhibits mitochondrial permeability transition pore opening. At 50 µM it inhibits dexamethasone- apoptosis in thymocytes, preventing the PARP cleavage and DEVDase (caspase-3 like) activity normally produced by these treatments.

VE: 1 * 1 mg

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Geranyl Pyrophosphate triammonium salt ≥95%

Lieferant: Cayman Chemical

Beschreibung: Geranyl pyrophosphate is an intermediate in the mevalonate pathway. It is formed from dimethylallyl pyrophosphate (DMAPP) and isopentenyl pyrophosphate by geranyl pyrophosphate synthase.

Aluminon, Supelco®

Artikel-Nr: (1.00128.0010)

Lieferant: Merck

Beschreibung: Aluminon, Supelco®

VE: 1 * 10 g

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Aluminon ACS, Sigma-Aldrich®

Lieferant: SIGMA ALDRICH MICROSCOPY

Beschreibung: Reagent for aluminium. Aurintricarboxylic acid readily polymerises in aqueous solution, forming a stable free radical that inhibits protein-nucleic acid interactions. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types. Its neuroprotective effect, perhaps due to its ability to prevent down-regulation of Ca²⁺ impermeable GluR2 receptors or to its ability to inhibit calpain, a Ca²⁺-activated protease that is activated during apoptosis.