Sie suchten nach: Tonbo Biosciences

Artikel-Nr: (35-8027-M001)

Lieferant: Tonbo Biosciences

Beschreibung: Goat anti-Human IgE (epsilon chain) - Affinity Pure, FITC Conjugate, min x w/bovine, mouse or rabbit serum proteins

VE: 1 * 1 mg

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Artikel-Nr: (30-8028-M001)

Lieferant: Tonbo Biosciences

Beschreibung: Goat anti-Human IgM (mu chain) - Affinity Pure, Biotin Conjugate

VE: 1 * 1 mg

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Artikel-Nr: (70-8024-M001)

Lieferant: Tonbo Biosciences

Beschreibung: Goat anti-Human IgE (epsilon chain) - Affinity Pure, min x w/bovine, mouse or rabbit serum proteins

VE: 1 * 1 mg

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Artikel-Nr: (50-8036-M001)

Lieferant: Tonbo Biosciences

Beschreibung: Goat anti-Rabbit IgG, secondary antibody, conjugated toSureLight® R-Phycoerythrin

VE: 1 * 1 mg

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Artikel-Nr: (72-8084-M001)

Lieferant: Tonbo Biosciences

Beschreibung: Donkey anti-Rabbit IgG (H&L) - Affinity Pure, HRP Conjugate, min x w/bovine, chicken, goat, guinea pig, hamster, horse, human, mouse, rat or sheep

VE: 1 * 1 mg

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Artikel-Nr: (67-4724-U100)

Lieferant: Tonbo Biosciences

Beschreibung: The C1.18.4 immunoglobulin is useful as an isotype-matched control. The C.1.18.4 immunolglobulin has an unknown binding specificity and is used as an isotype control for mouse IgG2a antibodies.

VE: 1 * 100 µG

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Artikel-Nr: (35-4732-U100)

Lieferant: Tonbo Biosciences

Beschreibung: The MPC-11 immunoglobulin is useful as an isotype-matched control. The MPC-11 immunolglobulin has an unknown binding specificity and is used as an isotype control for mouse IgG2b antibodies.

VE: 1 * 100 µG

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Artikel-Nr: (70-5921-U100)

Lieferant: Tonbo Biosciences

Beschreibung: The TER-119 antibody is named for the antigen to which it binds, a 52 kDa surface protein that is associated with glycophorin-A. TER-119 is considered to be a lineage marker for later stages of erythroid cell development, as its expression begins at the pro-erythroblast stage. TER-119 antigen is not expressed at either BFU-E or CFU-E stages, i.e. prior to the pro-erythroblast stage.

VE: 1 * 100 µG

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Artikel-Nr: (70-8028-M002)

Lieferant: Tonbo Biosciences

Beschreibung: Goat anti-Human IgM (mu chain) - Affinity Pure

VE: 1 * 2 mg

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Lieferant: Tonbo Biosciences

Beschreibung: The EBVCS-5 antibody is specific for human CD23, also known as the low affinity IgE receptor (FceRII), a 45 kDa type II transmembrane protein and member of the immunoglobulin superfamily. It is expressed on most B cells and is upregulated upon activation. It is also present on mantle zone B cells, eosinophils, monocytes and a subset of T cells and platelets. CD23 plays a role in B cell development and differentiation, and also functions to regulate IgE production. Soluble secreted forms of CD23 have been reported to bind IgE, stimulate release of pro-inflammatory cytokines from monocytes, and play a role in B cell differentiation.

Lieferant: Tonbo Biosciences

Beschreibung: The 3G3 antibody reacts with mouse Foxp3, a 50-55 kDa transcription factor which is a central regulator of T cell activity and is critical for the development and function of regulatory T cells (Tregs). Foxp3 is expressed at constitutively high levels in Treg cells, which are further identified as being CD4+ CD25+. In resting conventional T cells (CD4+ CD25-) Foxp3 expression is restricted, and upon TCR activation is expressed only transiently and in a small proportion of cells. However, the growth factor TGF-beta has been shown to induce expression of Foxp3 in naïve T cells, driving their development into Foxp3+ Tregs, which are called “induced” or “adaptive” Tregs. These cells are phenotypically similar to so-called “natural” Tregs (CD4+ CD25high Foxp3+) which originate in the thymus and comprise the majority of Treg cells. Tregs are critical for maintaining peripheral tolerance and are implicated in the development of autoimmunity. It is important to review the literature in choosing an antibody for the Foxp3 antigen in flow cytometry, as the potential for high background or non-specific staining may be observed. The 3G3 antibody may be used for intracellular detection of Foxp3 in cells from mouse and Rhesus macaque.

Artikel-Nr: (72-8114-M001)

Lieferant: Tonbo Biosciences

Beschreibung: Goat anti-Mouse IgG Fc - Affinity Pure, HRP Conjugate

VE: 1 * 1 mg

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Lieferant: Tonbo Biosciences

Beschreibung: The L17F12 antibody is specific for human CD5, a 67 kD transmembrane glycoprotein that is expressed on most thymocytes, mature T cells, and a subset of B cells. CD5 is a member of the scavenger receptor superfamily and is present on approximately 70% of normal peripheral blood lymphocytes. CD5 is involved in modulating antigen receptor signaling in both T and B cells and acts through binding of CD72, its receptor expressed on B cells.

Lieferant: Tonbo Biosciences

Beschreibung: The GK1.5 antibody reacts with mouse CD4, a 55 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4 is typically expressed on thymocytes, certain mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.

Lieferant: Tonbo Biosciences

Beschreibung: The RPA-T8 antibody is specific for the 32-34 kDa alpha chain of human CD8, known as CD8a or CD8 alpha. CD8a can form a homodimer (CD8 alpha-alpha), but is more commonly expressed as a heterodimer with a second chain known as CD8b or CD8 beta. CD8 acts as a co-receptor for antigen recognition and subsequent T cell activation that is initiated upon binding of the T cell receptor (TCR) to antigen-bearing MHC Class I molecules. The cytoplasmic domains of CD8 provide binding sites for the tyrosine kinase lck, facilitating intracellular signaling events that lead to T cell activation, development, and cytotoxic effector functions. CD8+ cytotoxic T cells (CTLs) play an important role in inducing cell death of tumor cells, as well as cells infected by virus, bacteria or parasites.

Artikel-Nr: (30-8016-M001)

Lieferant: Tonbo Biosciences

Beschreibung: Goat anti-Human IgA (alpha chain) - Affinity Pure, Biotin Conjugate

VE: 1 * 1 mg

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