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Lieferant: Apollo Scientific

Beschreibung: N-BOC-erythro-L-β-Methylphenylalanine 97%

Artikel-Nr: (H52099.03)

Lieferant: Thermo Scientific

Beschreibung: erythro-N-Boc-3,5-difluoro-L-phenylalanine epoxide 95%

VE: 1 * 1 g

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Artikel-Nr: (ACRO202660010)

Lieferant: Thermo Scientific

Beschreibung: β-Methyl-DL-phenylalanine hydrochloride 99%

VE: 1 * 1 g

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Artikel-Nr: (8.18289.0001)

Lieferant: Merck

Beschreibung: (+)-Ethyl-4,6-di-O-acetyl-2,3-dideoxy-α-D-erythro-hex-2-enopyranoside zur Synthese

VE: 1 * 1 g

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Artikel-Nr: (ENZOBMLSL2220025)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Negative control for D-<i>erythro</i>-MAPP

VE: 1 * 25 mg

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Lieferant: ENZO LIFE SCIENCES

Beschreibung: Alkaline ceramidase inhibitor

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Lieferant: ENZO LIFE SCIENCES

Beschreibung: Sphingosine kinase inhibitor

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Artikel-Nr: (ENZOBMLSL1430001)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: S1P receptor ligand.

VE: 1 * 1 mg

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Lieferant: ENZO LIFE SCIENCES

Beschreibung: Sphingosine precursor

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Lieferant: Thermo Scientific

Beschreibung: Appearance: White to cream Powder or waxy solid

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Artikel-Nr: (ENZOALX306017C500)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: D-erythro-Sphingosine-1-phosphate (caged) ≥95%

VE: 1 * 500 µG

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Lieferant: Cayman Chemical

Beschreibung: D-erythro-Sphingosine C-17 is a naturally-occurring but uncommon form of sphingosine, accounting for approximately 13% of the sphingosine in human skin.

Artikel-Nr: (ENZOBMLEI1550100)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Common component of cell membranes, often as phosphatidyl conjugates. Is a potent (IC50=1-3 µM) and selective inhibitor of protein kinase C. Inhibition is competitive with diacylglycerol, phorbol dibutyrate and Ca2+ and it also inhibits PKC activation by other lipids. It acts on an equimolar basis with 1,2-dioleoylglycerol and does not affect other kinases such as MLCK and PKA. It is active in intact cells and has been identified as an endogenous constituent in HL-60 cells, neutrophils, rat liver, and brain and mouse tissues. Other activities include inhibition of phosphatidate phosphohydrolase, Na+,K+-ATPase, CTP:phosphocholine cytidylyltransferase, calmodulin-dependent enzymes, binding of factor VII to tissue factor, binding of thyrotropin releasing hormone to its receptor and activation of EGF receptor kinase, phospholipase D and casein kinase II.

VE: 1 * 100 mg

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Lieferant: ENZO LIFE SCIENCES

Beschreibung: Ceramide-activated protein kinase activator.

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Lieferant: Cayman Chemical

Beschreibung: C18 Ceramide is an endogenous bioactive sphingolipid. It is the primary short-chain ceramide found in brain tissue whose synthesis is regulated by longevity-assurance homologue 1 (Lass1) in mice.

Lieferant: ENZO LIFE SCIENCES

Beschreibung: A biologically active, cell-permeable, but nonphysiologic ceramide analog. It activates protein phosphatase 2A and MAP kinase (MAPK/ERK), suppresses insulin-induced tyrosine phosphorylation and inhibits glycoprotein traffic by the secretory pathway. It inhibits diacylglycerol accumulation and phospholipase D activation in fibroblasts. It induces an arrest at the G0/G1 transition of the cell cycle (10μM) and causes apoptosis (15μM or greater) in Molt-4 leukemia cells.

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