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Artikel-Nr: (AATB112310O0)
Lieferant: AAT BIOQUEST
Beschreibung: The 12H7 monoclonal antibody binds to human CD123, a 70 kD single-pass type I membrane protein often located on the surface of macrophages, hematopoietic progenitors and dendritic cells. CD123 acts in vital cellular pathways, for instance, the cytokine-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands like CD131.
VE: 1 * 1 ST

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Artikel-Nr: (AATB22476)
Lieferant: AAT BIOQUEST
Beschreibung: Differentiates live yeast with intact membranes will stain fluorescent green, and dead yeast with damaged membranes will stain fluorescent red.
VE: 1 * 100 Tests


Artikel-Nr: (PRSI92-130)
Lieferant: ProSci Inc.
Beschreibung: Actin-Related Protein 8 (ACTR8) is a member of the Actin family. ACTR8 is the first example in actin family that was found to be associated with mitotic chromosomes. ACTR8 plays a vital role in the functional organisation of mitotic chromosomes. This protein is a proposed core component of the chromatin remodelling INO80 complex that is involved in transcriptional regulation, DNA replication and probable DNA repair, and it is required for the recruitment of INO80 (and probably the INO80 complex) to sites of DNA damage.
VE: 1 * 50 µG


Artikel-Nr: (PRSI91-984)
Lieferant: ProSci Inc.
Beschreibung: Cysteine Dioxygenase Type 1 (CDO1) is a mammalian non-heme iron enzyme that belongs to the cysteine dioxygenase family. CDO1 is highly expressed in the liver and placenta, and has a low expression in heart, brain and pancreas. CDO1 can also be detected in hepatoblastoma HepG2 cells. CDO1 catalyses the conversion of L-cysteine to cysteine sulfinic acid by incorporation of dioxygen. CDO1 is a vital regulator of cellular cysteine concentrations and has an essential role in maintaining the hepatic concentration of intracellular free cysteine within a proper narrow range. CDO1 is able to alter intracellular cysteine levels and glutathione levels.
VE: 1 * 50 µG


Artikel-Nr: (PRSI92-477)
Lieferant: ProSci Inc.
Beschreibung: Transforming growth factor beta-2 (TGF- beta 2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumours. Defects in TGFB2 may be a cause of non-syndromic aortic disease (NSAD).
VE: 1 * 50 µG


Artikel-Nr: (PRSI90-366)
Lieferant: ProSci Inc.
Beschreibung: NAD synthetase is an essential enzyme involved in both the de novo biosynthesis and salvage of NAD+, catalysing the final step of both pathways. Since NAD has a vital role in cell metabolism, the enzyme represents a valid target for the development of new antimycobacterial agents. It can use both glutamine or ammonia as a nitrogen source. Catalytic activity: ATP + deamido-NAD+ + L-glutamine + H₂O = AMP + diphosphate + NAD+ + L-glutamate.
VE: 1 * 50 µG


Artikel-Nr: (AATB2453)
Lieferant: AAT BIOQUEST
Beschreibung: Trypan blue, a diazo dye is a vital stain that colors dead tissues or cells blue.
VE: 1 * 10 mL


Artikel-Nr: (PRSI6543)
Lieferant: ProSci Inc.
Beschreibung: RASSF6 Antibody: RASSF family proteins are tumor suppressors that are frequently downregulated during the development of human cancer. RASSF6 (Ras association (RalGDS/AF-6) domain family member 6), a member of RASSF family, acts as a Ras effector protein / tumor suppressor. RASSF6 contains one Ras-associating domain and one SARAH domain. It is involved in the induction of apoptosis, through both caspase-dependent and caspase-independent pathways. Defects in RASSF6 may facilitate viral NF kappa -B pathway and may play a vital role in infection.
VE: 1 * 100 µG


Lieferant: EPPENDORF
Beschreibung: Eppendorf Protein LoBind-Platten sind für den Einsatz in der Proteomik oder anderen Bereichen der Proteinforschung konzipiert, in denen die Proteinkonzentration tendenziell sehr gering ist und die Probenrückgewinnung für die Testergebnisse von entscheidender Bedeutung ist.

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Artikel-Nr: (PRSIXW-8138)
Lieferant: ProSci Inc.
Beschreibung: FUNCTION: Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume.
SIMILARITY: Belongs to the SLC12A transporter family.
SUBCELLULAR LOCATION: Membrane; multi-pass membrane protein.
TISSUE SPECIFICITY: Expressed in many tissues.
VE: 1 * 50 µG


Artikel-Nr: (ICNA0855951)
Lieferant: MP Biomedicals
Beschreibung: Product is the lyophilized powder of rat IgG and buffer salts.IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections. The total protein is determined using the Biuret procedure, with bovine albumin as the standard. Each vial is overfilled by approximately 10 percent so that a minimum of 20 mg of rat IgG is obtained upon reconstitution.
VE: 1 * 20 mg


Artikel-Nr: (PRSI55-771)
Lieferant: ProSci Inc.
Beschreibung: HAUS3 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).
VE: 1 * 400 µl

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Artikel-Nr: (PRSI92-521)
Lieferant: ProSci Inc.
Beschreibung: Interleukin 2 (IL 2), also termed T-cell growth factor, is a member of the cytokine family which includes IL-4, IL-7, IL-9, IL-15 and IL-21. Each member of this family has a four alpha helix bundle. IL-2 signals through the IL-2 receptor, a complex consisting of tree subunits, termed alpha, beta and gamma. The IL-2 R gamma is shared by cytokine receptors of all members of cytokine family. Mature mouse IL­2 shares 56% and 73% aa sequence identity with human and rat IL­2, respectively. IL-2 is produced by CD4+ T cell, CD8+ T cells, gamma delta T cells, B cells, dendritic cells and eosinophils, and plays a vital role in key function of the immune system, tolerance and immunity, primarily via its potent stimulatory activity for T cells.Thus, IL­2 may be a key cytokine in the natural suppression of autoimmunity.
VE: 1 * 50 µG


Artikel-Nr: (AATB2452)
Lieferant: AAT BIOQUEST
Beschreibung: Trypan blue, a diazo dye is a vital stain that colors dead tissues or cells blue.
VE: 1 * 10 g


Lieferant: Agilent
Beschreibung: These gas regulators ensure that ICP-MS applications and methods are carried out with the consistent and stable gas flows. Effective gas regulation is vital for ensuring that ICP-MS systems operate from a stable basis allowing industry-leading levels of sensitivity to be achieved in relevant systems.

Lieferant: MP Biomedicals
Beschreibung: Cytochrome C is an electron-carrying mitochondrial protein. The transition of Cytochrome C between the ferrous and ferric states within the cell makes it an efficient biological electron-transporter and it plays a vital role in cellular oxidations in both plants and animals. It is generally regarded as a universal catalyst of respiration, forming an essential electron-bridge between the respirable substrates and oxygen.

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