Sie suchten nach: syn-Benzaldehydoxim

Lieferant: Merck

Beschreibung: syn-Benzaldehydoxim, Sigma-Aldrich®

Artikel-Nr: (8.20234.0025)

Lieferant: Merck

Beschreibung: Benzaldehydoxim, Sigma-Aldrich®

VE: 1 * 25 mL

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Artikel-Nr: (APOSOR4290-100G)

Lieferant: Apollo Scientific

Beschreibung: Benzaldehydoxim 90%

VE: 1 * 100 g

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Lieferant: Merck

Beschreibung: Acetaldehydoxim (Gemisch der syn- und anti-Isomeren) zur Synthese, Sigma-Aldrich®

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Lieferant: Apollo Scientific

Beschreibung: syn-2-Pyridincarbaldehydoxim

Artikel-Nr: (32635-100MG)

Lieferant: Merck

Beschreibung: Organic Standard, Dimethachlor Metabolite SYN 530561

VE: 1 * 100 mg

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Lieferant: Thermo Scientific

Beschreibung: syn-2-Pyridincarbaldehydoxim 99+%

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Lieferant: Thermo Scientific

Beschreibung: Acetaldehydoxim (Gemisch der syn- und anti-Isomeren) 99%

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Lieferant: Thermo Scientific

Beschreibung: cis-Dicyclohexyl-18-krone-6 (Gemisch aus syn-cis- und anti-cis-Isomer) 98%

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Lieferant: Thermo Scientific

Beschreibung: Acetaldehydoxim (Gemisch der syn- und anti-Isomeren) 99%

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Artikel-Nr: (USBI145243)

Lieferant: US Biological

Beschreibung: Anti-SYP Mouse Monoclonal Antibody [clone: Syn-58]

VE: 1 * 100 µG

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Lieferant: ENZO LIFE SCIENCES

Beschreibung: Synuclein was originally identified in Torpedo californica as a small neuroprotein that localized to the nuclear envelope of neurons and to presynaptic nerve termini. The human homolog was initially termed NACP, a precursor protein to NAC (Non-Ab Component), because of its prevalence in amyloid plaques in Alzheimer’s patients. Later, NACP was recognized as being alpha-Synuclein (alpha-SYN), a 14kDa protein, belonging to the synuclein family of phosphoproteins that also includes: betalpha-SYNuclein, gammalpha-SYNuclein, and synoretin.
alpha-SYN is recognized as a key component in the development and diagnosis of neurodegenerative synucleinopathic diseases (NSDs), such as Alzheimer’s and Parkinson’s disease. In the past five years, several genetic and post-translational modifications to alpha-SYN have been elucidated that have been linked to its collaboration in the formation of the classical Lewy bodies (LBs) or Lewy neurites that are associated with neurodegeneration. A study that shed more light on the neurogenesis of autorecessive synucleinopathies (ARSs) was the finding that alpha-SYN accumulation can occur due to mutations in the E3 ubiquitin ligase.
ARSs only account for a small percentage of NSD. Thus the illustration that alpha-SYN has a high susceptibility to tyrosine nitration may be the key component in understanding the formation of LBs. Due to the chemical structure of alpha-SYN, tyrosine nitration readily leads to the formation of oligomers via covalent O,O’-dityrosine bonds (cross-linking). Nitrosylated, wild-type, alpha-SYN products thus form SDS-insoluble, heat-stable aggregates in vitro that may account for alpha-SYN inclusions in all forms of NSDs.

Neuer Artikel bei VWR!

Artikel-Nr: (GD1001-RV)

Lieferant: Charles River Laboratories Cell Solutions

Beschreibung: AAV1/2 Vector with CMV promoter, human A53T alpha-synuclein, WPRE, bovine growth hormone (BGH), and polyadenylation sequence.

VE: 1 * 25 µl

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Artikel-Nr: (USBI032289-PE)

Lieferant: US Biological

Beschreibung: Anti-ATP5S Rabbit Polyclonal Antibody (PE (Phycoerythrin))

VE: 1 * 200 µl

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Artikel-Nr: (USBI032289-HRP)

Lieferant: US Biological

Beschreibung: Anti-ATP5S Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

VE: 1 * 200 µl

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Artikel-Nr: (USBIN2950-01D)

Lieferant: US Biological

Beschreibung: Anti-NOS1 Rabbit Polyclonal Antibody

VE: 1 * 100 µl

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