Sie suchten nach: UNC-2025

Artikel-Nr: (ACRO467881000)

Lieferant: Thermo Scientific

Beschreibung: Chemical probes can be used to help establish the
relationship between a molecular target and the broader
biological consequences of modulating that target in cells
or organisms.

VE: 1 * 100 mg

Sale!

Artikel-Nr: (APOSOR323195-100MG)

Lieferant: Apollo Scientific

Beschreibung: UNC 1215

VE: 1 * 100 mg

Sale!

Artikel-Nr: (USBI146259)

Lieferant: US Biological

Beschreibung: Anti-UNC93B1 Rabbit Polyclonal Antibody

VE: 1 * 100 µG

Sale!

Artikel-Nr: (BOSSBS-11840R-CY3)

Lieferant: Bioss

Beschreibung: Zygin 2 is a 353 amino acid cytoplasmic protein that belongs to the zygin family. Zygin 2 is found as a difulfide-linked homodimer but may for heterodimers with FEZ1. the plasma membrane to the cytoplasm by activation of PKC zeta. PKC zeta also enhances zygin 1 interaction with UFD2 and polyubiquitination. Expressed mainly in brain, zygin 1 is a mammalian ortholog of Caenorhabditis elegans UNC-76 and is able to restore partial locomotion and axonal fasciculation to C. elegans UNC-76 mutants, which suggest a functional role in axonal outgrowth. As component of the network of molecules that regulate cellular morphology and axon guidance machinery, zygin 1 may also be involved in microtubule associated transport and transcriptional regulation. Mutations in the gene encoding zygin 1 may be linked to the pathogenesis of schizophrenia. Zygin 1 exists as two alternatively spliced isoforms that are designated isoform long and isoform short.

VE: 1 * 100 µl

Sale!

Artikel-Nr: (BOSSBS-11840R-HRP)

Lieferant: Bioss

Beschreibung: Zygin 2 is a 353 amino acid cytoplasmic protein that belongs to the zygin family. Zygin 2 is found as a difulfide-linked homodimer but may for heterodimers with FEZ1. the plasma membrane to the cytoplasm by activation of PKC zeta. PKC zeta also enhances zygin 1 interaction with UFD2 and polyubiquitination. Expressed mainly in brain, zygin 1 is a mammalian ortholog of Caenorhabditis elegans UNC-76 and is able to restore partial locomotion and axonal fasciculation to C. elegans UNC-76 mutants, which suggest a functional role in axonal outgrowth. As component of the network of molecules that regulate cellular morphology and axon guidance machinery, zygin 1 may also be involved in microtubule associated transport and transcriptional regulation. Mutations in the gene encoding zygin 1 may be linked to the pathogenesis of schizophrenia. Zygin 1 exists as two alternatively spliced isoforms that are designated isoform long and isoform short.

VE: 1 * 100 µl

Sale!

Artikel-Nr: (BOSSBS-11840R-A647)

Lieferant: Bioss

Beschreibung: Zygin 2 is a 353 amino acid cytoplasmic protein that belongs to the zygin family. Zygin 2 is found as a difulfide-linked homodimer but may for heterodimers with FEZ1. the plasma membrane to the cytoplasm by activation of PKC zeta. PKC zeta also enhances zygin 1 interaction with UFD2 and polyubiquitination. Expressed mainly in brain, zygin 1 is a mammalian ortholog of Caenorhabditis elegans UNC-76 and is able to restore partial locomotion and axonal fasciculation to C. elegans UNC-76 mutants, which suggest a functional role in axonal outgrowth. As component of the network of molecules that regulate cellular morphology and axon guidance machinery, zygin 1 may also be involved in microtubule associated transport and transcriptional regulation. Mutations in the gene encoding zygin 1 may be linked to the pathogenesis of schizophrenia. Zygin 1 exists as two alternatively spliced isoforms that are designated isoform long and isoform short.

VE: 1 * 100 µl

Sale!

Artikel-Nr: (USBIM2196-85G)

Lieferant: US Biological

Beschreibung: Anti-UNC13D Goat Polyclonal Antibody

VE: 1 * 50 µG

Sale!

Artikel-Nr: (USBIU1610-03)

Lieferant: US Biological

Beschreibung: Anti-FERMT3 Rabbit Polyclonal Antibody

VE: 1 * 100 µG

Sale!

Artikel-Nr: (USBI133549)

Lieferant: US Biological

Beschreibung: Anti-SMAP1 Mouse Polyclonal Antibody

VE: 1 * 50 µG

Sale!

Artikel-Nr: (LAUDL001255)

Lieferant: LAUDA

Beschreibung: Kältethermostate mit Kurztext-Menüsteuerung für benutzerfreundliche Bedienung. Verschiedene Schnittstellenmodule als Zubehör erhältlich. Alle Modelle sind mit Luft- oder Wasserkühlung erhältlich.

VE: 1 * 1 ST

Neuer Artikel bei VWR! Sale!

Artikel-Nr: (USBIU0893-50A-AP)

Lieferant: US Biological

Beschreibung: Anti-UNC5C Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))

VE: 1 * 200 µl

Sale!

Artikel-Nr: (BOSSBS-11840R-CY5)

Lieferant: Bioss

Beschreibung: Zygin 2 is a 353 amino acid cytoplasmic protein that belongs to the zygin family. Zygin 2 is found as a difulfide-linked homodimer but may for heterodimers with FEZ1. the plasma membrane to the cytoplasm by activation of PKC zeta. PKC zeta also enhances zygin 1 interaction with UFD2 and polyubiquitination. Expressed mainly in brain, zygin 1 is a mammalian ortholog of Caenorhabditis elegans UNC-76 and is able to restore partial locomotion and axonal fasciculation to C. elegans UNC-76 mutants, which suggest a functional role in axonal outgrowth. As component of the network of molecules that regulate cellular morphology and axon guidance machinery, zygin 1 may also be involved in microtubule associated transport and transcriptional regulation. Mutations in the gene encoding zygin 1 may be linked to the pathogenesis of schizophrenia. Zygin 1 exists as two alternatively spliced isoforms that are designated isoform long and isoform short.

VE: 1 * 100 µl

Sale!

Artikel-Nr: (USBI043613)

Lieferant: US Biological

Beschreibung: Anti-UNC5C Rabbit Polyclonal Antibody

VE: 1 * 200 µl

Sale!

Artikel-Nr: (BOSSBS-11449R-HRP)

Lieferant: Bioss

Beschreibung: The C. elegans protein Unc-115 mediates axon guidance by modulating the growth cone Actin cytoskeleton in response to signals received by growth cone receptors. The mammalian homolog of Unc-115 is the Actin-binding LIM protein family member 1 (ABLIM1, also designated Limatin). The ABLIM1 protein has an N-terminal domain that contains four double zinc finger motifs, which conform to the LIM motif consensus sequence. ABLIM1 binds to F-Actin through a dematin-like domain and is expressed in retina, brain and muscle tissue. There are four known isoforms of ABLIM1. The gene encoding ABLIM1 maps to a region of chromosome 10 associated with frequent loss of heterozygosity in human tumors, thus identifying ABLIM1 as a candidate tumor suppressor gene. ABLIM2 and ABLIM3 show highest expression in muscle and neuronal tissues, bind to F-Actin, and are localized on stress fibers. They also have been shown to enhance STARS (striated muscle activator of Rho signaling) dependent activation of serum-response factor (SRF), thereby modulating transcription.

VE: 1 * 100 µl

Sale!

Artikel-Nr: (BOSSBS-11449R-A647)

Lieferant: Bioss

Beschreibung: The C. elegans protein Unc-115 mediates axon guidance by modulating the growth cone Actin cytoskeleton in response to signals received by growth cone receptors. The mammalian homolog of Unc-115 is the Actin-binding LIM protein family member 1 (ABLIM1, also designated Limatin). The ABLIM1 protein has an N-terminal domain that contains four double zinc finger motifs, which conform to the LIM motif consensus sequence. ABLIM1 binds to F-Actin through a dematin-like domain and is expressed in retina, brain and muscle tissue. There are four known isoforms of ABLIM1. The gene encoding ABLIM1 maps to a region of chromosome 10 associated with frequent loss of heterozygosity in human tumors, thus identifying ABLIM1 as a candidate tumor suppressor gene. ABLIM2 and ABLIM3 show highest expression in muscle and neuronal tissues, bind to F-Actin, and are localized on stress fibers. They also have been shown to enhance STARS (striated muscle activator of Rho signaling) dependent activation of serum-response factor (SRF), thereby modulating transcription.

VE: 1 * 100 µl

Sale!

Artikel-Nr: (BOSSBS-11449R-CY5)

Lieferant: Bioss

Beschreibung: The C. elegans protein Unc-115 mediates axon guidance by modulating the growth cone Actin cytoskeleton in response to signals received by growth cone receptors. The mammalian homolog of Unc-115 is the Actin-binding LIM protein family member 1 (ABLIM1, also designated Limatin). The ABLIM1 protein has an N-terminal domain that contains four double zinc finger motifs, which conform to the LIM motif consensus sequence. ABLIM1 binds to F-Actin through a dematin-like domain and is expressed in retina, brain and muscle tissue. There are four known isoforms of ABLIM1. The gene encoding ABLIM1 maps to a region of chromosome 10 associated with frequent loss of heterozygosity in human tumors, thus identifying ABLIM1 as a candidate tumor suppressor gene. ABLIM2 and ABLIM3 show highest expression in muscle and neuronal tissues, bind to F-Actin, and are localized on stress fibers. They also have been shown to enhance STARS (striated muscle activator of Rho signaling) dependent activation of serum-response factor (SRF), thereby modulating transcription.

VE: 1 * 100 µl

Sale!