Sie suchten nach: VITAL+SCIENTIFIC

Artikel-Nr: (PRSI91-112)

Lieferant: ProSci Inc.

Beschreibung: Human Deoxyhypusine Synthase (DHS) is vital for the first step of hypusine biosynthesis. DHS catalyzes the NAD-dependent oxidative cleavage of spermidine, the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.

VE: 1 * 50 µG

Sale!

Artikel-Nr: (PRSI90-367)

Lieferant: ProSci Inc.

Beschreibung: NAD synthetase is an essential enzyme involved in both the de novo biosynthesis and salvage of NAD+, catalyzing the final step of both pathways. Since NAD has a vital role in cell metabolism, the enzyme represents a valid target for the development of new antimycobacterial agents. It was shown to be induced by heat shock, salt stress, oxidative stress, glucose limitation and oxygen limitation and is involved in biological processes like stress response and sporulation resulting in formation of a cellular spore. Catalytic activity: ATP + deamido-NAD+ + NH3 = AMP + diphosphate + NAD+

VE: 1 * 50 µG

Sale!

Artikel-Nr: (PRSI55-200)

Lieferant: ProSci Inc.

Beschreibung: Vitamin A metabolism is important for vital processes such as vision, embryonic development, cell differentiation, and membrane and skin protection. The protein encoded by this gene is a key enzyme in beta-carotene metabolism to vitamin A. It catalyzes the oxidative cleavage of beta,beta-carotene into two retinal molecules.

VE: 1 * 400 µl

Neuer Artikel bei VWR! Sale!

Artikel-Nr: (BOSSBS-4980R-A680)

Lieferant: Bioss

Beschreibung: Human immunodeficiency virus (HIV) is a retrovirus that can lead to a condition in which the immune system begins to fail, leading to opportunistic infections. HIV primarily infects vital cells in the human immune system such as helper T cells(specifically CD4+ T cells), macrophages and dendritic cells. HIV infection leads to low levels of CD4+ T cells through three main mechanisms: firstly, direct viral killing of infected cells; secondly, increased rates of apoptosis in infected cells; and thirdly, killing of infected CD4+ T cells by CD8 cytotoxic lymphocytes that recognize infected cells. When CD4+ T cell numbers decline below a critical level, cell-mediated immunity is lost, and the body becomes progressively more susceptible to opportunistic infections. HIV was classified as a member of the genus Lentivirus, part of the family of Retroviridae. Lentiviruses have many common morphologies and biological properties. Many species are infected by lentiviruses, which are characteristically responsible for long-duration illnesses with a long incubation period. Lentiviruses are transmitted as single-stranded, positive-sense, enveloped RNA viruses. Upon entry of the target cell, the viral RNA genome is converted to double-stranded DNA by a virally encoded reverse transcriptase that is present in the virus particle. This viral DNA is then integrated into the cellular DNA by a virally encoded integrase so that the genome can be transcribed. Once the virus has infected the cell, two pathways are possible: either the virus becomes latent and the infected cell continues to function, or the virus becomes active and replicates, and a large number of virus particles are liberated that can then infect other cells.

VE: 1 * 100 µl

Sale!

Lieferant: Dino-Lite / IDCP B.V.

Beschreibung: High Speed Real Time models connect directly to a computer monitor/ VGA screen via a VGA (D-SUB) connector. Ideal for use in situations where real time images are vital.

Artikel-Nr: (PRSI7257)

Lieferant: ProSci Inc.

Beschreibung: FOXA2 Antibody: FOXA2 is one of three members of the FOXA family, a subset of the forkhead family of transcription factors which play vital roles in development. FOXA2 was initially identified through library screening as a closely related homolog of FOXA1. Both FOXA2 and FOXA1 act as transcriptional activators in adult liver and also play a role in body axis formation, neural tube patterning and definitive endoderm formation during gastrulation.

VE: 1 * 100 µG

Sale!

Artikel-Nr: (PRSI33-064)

Lieferant: ProSci Inc.

Beschreibung: Autophagy is the cellular mechanism of degradation and turnover of unnecessary or dysfunctional cellular components. The unneeded components are engulfed in vesicles called autophagosomes, where they are broken down and recycled. The ‘autophagy-related gene’ ATG4B is a regulator of autophagasome maturation. The microtubule-associated protein LC3-I is lipidated (called LC3-II in its lipidated state) and recruited to the autophagosomal membrane where it is of vital importance in the maturation of autophagosomes. ATG4B regulates LC3-II availability by modulating LC3-I lipidation.

VE: 1 * 100 µG

Neuer Artikel bei VWR! Sale!

Artikel-Nr: (AATB22476)

Lieferant: AAT BIOQUEST

Beschreibung: Differentiates live yeast with intact membranes will stain fluorescent green, and dead yeast with damaged membranes will stain fluorescent red.

VE: 1 * 100 Tests

Sale!

Artikel-Nr: (PRSI92-228)

Lieferant: ProSci Inc.

Beschreibung: UBA5 is a member of the ubiquitin-activating E1 family and UBA5 subfamily. Ubiquitin and ubiquitin-like proteins are recognised as covalently conjugated to various cellular substrates by a three-step enzymatic pathway. The ubiquitin-activating enzyme (E1) has a vital role in the first step of ubiquitination pathway to activate ubiquitin or ubiquitin-like proteins. UBA5 activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy thioester bond. UBA5 is located primarily in cytoplasm, while it generally localises to the nucleus in presence of SUMO2.

VE: 1 * 50 µG

Sale!

Artikel-Nr: (PRSI92-130)

Lieferant: ProSci Inc.

Beschreibung: Actin-Related Protein 8 (ACTR8) is a member of the Actin family. ACTR8 is the first example in actin family that was found to be associated with mitotic chromosomes. ACTR8 plays a vital role in the functional organisation of mitotic chromosomes. This protein is a proposed core component of the chromatin remodelling INO80 complex that is involved in transcriptional regulation, DNA replication and probable DNA repair, and it is required for the recruitment of INO80 (and probably the INO80 complex) to sites of DNA damage.

VE: 1 * 50 µG

Sale!

Lieferant: MP Biomedicals

Beschreibung: Brilliant Cresyl Blue is a supravital stain used in hematology for demonstrating and counting reticulocytes and platelets. It is also used as a vital stain for demonstrating the mucous secretions of the marine coelomates.

Artikel-Nr: (AATB100420O1)

Lieferant: AAT BIOQUEST

Beschreibung: SK3 is an anti-human monoclonal antibody that recognizes the CD4 antigen. CD4 (alternatively called T4 or Leu3a) is a 55 kD member of the Ig superfamily that is located on the surface of cells such as macrophages, T cells and granulocytes. CD4 has been associated with important biological processes such as membrane organization, specifically fusion of virus membrane with host plasma membrane. Furthermore, it is involved with vital cellular pathways, for example, the T cell receptor signaling pathway, enzyme linked receptor protein signaling pathway and cytokine-mediated signaling pathway.

VE: 1 * 1 ST

Neuer Artikel bei VWR! Sale!

Lieferant: AAT BIOQUEST

Beschreibung: Cells utilise a wide variety of phosphate (Pi) and polyphosphate esters as enzyme substrates, second messengers, membrane structural components and vital energy reservoirs.

Artikel-Nr: (720-1339)

Lieferant: BAYER VITAL

Beschreibung: Reagent strips for urinalysis tests.

VE: 1 * 50 ST

Sale!

 This is a MarketSource item. Additional charges may apply

Artikel-Nr: (NEWPMAT566-BL)

Lieferant: NEW PIG

Beschreibung: Multi-sheet floor mat grabs grime from shoes and wheels to keep dirt out of offices, cleanrooms and other areas where clean floors are vital.

VE: 1 * 4 ST

Sale!

Artikel-Nr: (PRSI55-771)

Lieferant: ProSci Inc.

Beschreibung: HAUS3 is 1 of 8 subunits of the 390-kD human augmin complex, or HAUS complex. The augmin complex was first identified in Drosophila, and its name comes from the Latin verb 'augmentare,' meaning 'to increase.' The augmin complex is a microtubule-binding complex involved in microtubule generation within the mitotic spindle and is vital to mitotic spindle assembly (Goshima et al., 2008 [PubMed 18443220]; Uehara et al., 2009 [PubMed 19369198]).

VE: 1 * 400 µl

Neuer Artikel bei VWR! Sale!