Sie suchten nach: 5Z-7-Oxozeaenol

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Inhibitor of the JNK/p38 pathways. Inhibits anisomycin-induced but not TNF-induced JNK/p38 activation. Potent protein kinase inhibitor
>A naturally isolated cell-permeable fungal resorcylic lactone that acts as a selective and highly potent inhibitor against the MAPKKK TAK1 activity (IC50 = 8nM) in an ATP-competitive and irreversible manner; also inhibits MEK1 (IC50 = 411nM) and three other MAPKKKs (IC50 ≥268 nM against MEKK1, ASK1, and MEKK4) but at much higher concentrations. Shown to inhibit IL-1-induced/TAK1-mediated, but not H2O2-induced/TAK1-independent, JNK and p38 phosphorylation in 293 cells.

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Lieferant: Apollo Scientific

Beschreibung: LL-Z-1640-2

Artikel-Nr: (APOSOR450084-1G)

Lieferant: Apollo Scientific

Beschreibung: (5Z)-5-(Ethoxymethylene)-2-thioxo-1,3-thiazolidin-4-one

VE: 1 * 1 g

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Lieferant: Cayman Chemical

Beschreibung: Arachidonic acid (Item No. 90010) is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes.

Artikel-Nr: (ENZOBMLFA0240001)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Arachidonic acid analog.

VE: 1 * 1 mg

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Artikel-Nr: (ENZOBMLD1220050)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Arachidonic acid metabolite.

VE: 1 * 50 µG

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Artikel-Nr: (ENZOBMLEE110050)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Biosynthesis via liver and renal cytochrome P-450. Induces glucagon release from pancreatic islets. Vasodilator in intestinal microcirculation. Inhibits Na+K+-ATPase. Urinary excretion in humans is increased during pregnancy-induced hypertension.

VE: 1 * 50 µG

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Artikel-Nr: (ENZOBMLH1120050)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Biosynthesis in psoriatic skin and corneal epithelial cells via cytochrome P-450. More potent than 12(S)-HETE in inducing human leukocyte chemokinesis and aggregation. Proinflammatory effects in human skin. Inhibits renal, cardiac and corneal Na+,K+-ATPase. Reduces intraocular pressure.

VE: 1 * 50 µG

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Artikel-Nr: (ENZOBMLHP0150050)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Primary metabolite of arachidonic acid via the 15-lipoxygenase pathway. Inhibits prostacyclin synthase and arachidonic acid induced platelet aggregation. Endogenous TRPV1 agonist.

VE: 1 * 50 µG

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Artikel-Nr: (ENZOBMLHP0120050)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Primary metabolite of arachidonic acid via the 12-lipoxygenase pathway. Inhibits thromboxane synthase. Inhibits platelet aggregation via activation of guanylate cyclase (100% at 5µM). Stimulates leukotriene biosynthesis. Potent and selective inhibitor of Ca2+-calmodulin-dependent protein kinase II (IC50=0.7µM). Endogenous TRPV1 agonist (Ki=0.35µM).

VE: 1 * 50 µG

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Artikel-Nr: (ENZOALX270515M005)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Pim1 inhibitor

VE: 1 * 5 mg

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Artikel-Nr: (ENZOBMLH0080050)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Activator of PKC and PPARα.

VE: 1 * 50 µG

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Lieferant: ENZO LIFE SCIENCES

Beschreibung: Biosynthesis in human neutrophils, eosinophils and reticulocytes. Most abundant eicosanoid in human bronchi. Regulates T lymphocyte mitogenesis. Induces immunosupression. Stimulates migration of capillary endothelial cells and neovascularisation.

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Artikel-Nr: (CAYM10010377-1)

Lieferant: Cayman Chemical

Beschreibung: Arachidonsäure

VE: 1 * 1 ST

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Artikel-Nr: (ENZOBMLH0120050)

Lieferant: ENZO LIFE SCIENCES

Beschreibung: Biosynthesis by platelet 12-lipoxygenase. Chemotactic and chemokinetic for PMNL2 and for vascular smooth muscle cells. Antiproliferative effect on smooth muscle cells. Second messenger in angiotensin induced aldosterone production. Induces endothelial cell retraction and tumor cell adhesion.

VE: 1 * 50 µG

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Lieferant: Cayman Chemical

Beschreibung: (±)11(12)-EET is biosynthesized in rat and rabbit liver microsomes by CYP450. (±)11(12)-EET has been shown, along with (±)8(9)-EET, to play a role in the recovery of depleted Ca²⁺ pools in cultured smooth muscle cells.